Biliary involvement during abdominal tuberculosis is extremely uncommon and represents a challenging diagnosis that can easily be mistaken for a malignant etiology. We report the case of a 40 years old male who presented with anorexia, chronic abdominal pain, and progressive obstructive jaundice. Abdominal computed tomography demonstrated distal narrowing with wall thickening of the main biliary duct, along with enlarged lymph nodes and signs of portal hypertension. Abdominal magnetic resonance imaging showed a long distal biliary stricture, suggestive of malignancy, with dilated intrahepatic radicles. The diagnosis of cholangiocarcinoma was initially suggested. However, given his young age and other imaging findings, the patient underwent laparoscopic biopsy which revealed epithelioid cell granuloma with caseating necrosis consistent with tuberculous origin.
Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted images showed the classic eye of the tiger sign seen in pantothenate kinase-associated neurodegeneration.
Introduction: Descending necrotizing mediastinitis is a rare and fatal condition that results from the spread of cervicofacial infections to the mediastinum. Early and appropriate management is needed to reduce mortality and morbidity rates. Imaging, especially CT, plays a central role in the diagnosis, treatment, and monitoring of patients. This study is aimed at assessing the role of computed tomography in diagnosing and planning the management of DNM. Material and methods: This is an 8-year retrospective study on 11 patients who fulfilled the ESTRERA criteria. All the patients underwent thoracic radiography along with an enhanced cervicothoracic CT scan. Results: Median age was 34 years with a sex-ratio of 1.75. 4 patients had diabetes. The primary oropharyngeal infection was an odontogenic abscess in most cases. The reported symptoms were mainly thoracic pain and fever. Thoracic radiography and cervicothoracic CT scan confirmed the diagnosis and showed different findings. 7 patients were diagnosed with type I DNM, 1 patient with type IIA and 3 patients with type IIB. Conclusion: DNM is a medico-surgical emergency where imaging, in particular CT, plays an essential role in establishing the diagnosis and guiding the surgical approach to ensure optimal patient care.
Fifteenth of Cronobacter sakazakii were obtained from previous studies isolates
were (infant formula, spinal fluid and bloods). The newborn mice and number was 15
obtaining healthy newborn mice from the Iraqi Center for Cancer and Medical Genetics
whose ages ranged between 10-17 days and their weights 8.5 ± 1.25 gm, were divided into
3 groups. The samples were cut and placed in formalin, then placed in stabilizer and
concentrations of alcohol (70%, 80%, 90%,100%) to complete dehydration after they were
leached with xylene, embedded the samples paraffin wax (58°C) and sectioning the with
thickness (5) micrometer and stained with Haematoxylin and Eosin stain. The results of
an increase in the weight of the brain organ for the mice compared to the control
treatment and this increase was significant at the probability level p≤0.05 and the
results showed the inflammatory response of the brain of large number of
polymorphnuclear cells and mononuclear cells as well as congested blood vessels with an
increase in the size of endothelial cells. The presence of bleeding congestion and
shrinking of nerve cells in the area of the cerebral cortex, gliosis (neuroma), was more
prominent in the molecular layer in the brain of the newborn mice fed at a concentration
of 105 cells and the occurrence of oedema ,the presence of haemorrhage in both
concentrations of dosed newborn mice and necrosis of the choroid plexus concentration103
and 105 cells.
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