Pseudomonas aeruginosa is the most common gram negative bacteria associated with nosocomial infections. In recent years, a considerable increase in the prevalence and multidrug resistance (MDR) P. aeruginosa has been noticed with high morbidity and mortality. The present study was conducted to find out the current antimicrobial susceptibility pattern of P. aeruginosa isolates obtained from clinical samples at our hospital. MATERIALS AND METHODS: Pseudomonas aeruginosa isolated from various clinical specimens during March 2013 to February 2014 were included in the study. Isolates were identified by conventional tests and antibiotic susceptibility was determined by disc diffusion method according to CLSI guidelines. RESULTS: A total of 159 Pseudomonas aeruginosa isolates were included in this study. Majority of isolates was found in pus followed by urine. Highest susceptibility was shown towards imipenem followed by amikacin and least susceptibility was shown towards cephalosporins. Multi-drug resistance was shown by 21isolates tested. CONCLUSION: P. aeruginosa showed higher rate of resistance towards commonly used antibiotics which may be due to indiscriminate prescription patterns. To prevent the selection and spread of the resistant bacteria, it is critically important to have strict antibiotic policies.
Background: Urinary tract infections (UTI) are one of the most common infectious diseases diagnosed in outpatients as well as in hospitalized patients, and can lead to significant mortality. Several rapid methods have been developed in diagnosing urinary tract infections such as microscopic examination, chemical tests, and automated systems. Thus, in this study we aimed at determining pyuria in suspected UTI patients and their association with uropathogen. Materials and Methods: A total of 379 clean catch mid-stream urine samples were collected in sterile containers. Manual microscopy is used to determine pyuria. All the urine samples inoculated on routine bacteriological media. Results: Out of 379 urine samples, 181 yielded significant bacterial growth. Patients belonged to age group 21-30 were more commonly had significant growth followed by 11-20 years age group. Escherichia coli was the most common organism isolated. Majority of urine specimens which showed plenty of pus cells per high power field yielded significant growth. Escherichia coli was most commonly associated with pyuria. Conclusion: As the number of pus cells in urine increases, the chance of yielding significant bacterial growth is also high. Overall, significant pyuria was observed among specimens yielded Gram negative bacilli than Gram positive cocci. Among Gram negative bacilli, Escherichia coli was most commonly accompanied with pyuria.
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