Biomimetic membrane materials have
been widely explored and developed
for drug loading and tissue engineering applications due to their
excellent biocompatibility and abundant reaction sites. However, novel
cytomembrane mimics have been lacking for a long time. In this study,
black phosphorus (BP) was used as the foundation for a new generation
of promising cytomembrane mimics due to its multiple similarities
to cytomembranes. Inspired by the dual function of endotoxins on membranes,
we prepared a BP-based cytomembrane mimic with controllable antibacterial
ability via electrostatic interaction between BP and [1-pentyl-1-quaternary
ammonium-3-vinyl-imidazole]Br ([PQVI]Br). The release of PQVI could
be manipulated in different conditions by adjusting the electrostatic
force, thereby achieving controllable antibacterial ability. This
report confirms the possibility of using BP as a new material to mimic
cytomembranes and provides a new concept of controllable antibacterial
action based on endotoxins.
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