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Robust control design for quantum systems has been recognized as a key task in quantum information technology, molecular chemistry and atomic physics. In this paper, an improved differential evolution algorithm of msMS DE is proposed to search robust fields for various quantum control problems. In msMS DE, multiple samples are used for fitness evaluation and a mixed strategy is employed for mutation operation. In particular, the msMS DE algorithm is applied to the control problem of open inhomogeneous quantum ensembles and the consensus problem of a quantum network with uncertainties. Numerical results are presented to demonstrate the excellent performance of the improved DE algorithm for these two classes of quantum robust control problems. Furthermore, msMS DE is experimentally implemented on femtosecond laser control systems to generate good signals of twophoton absorbtion and control fragmentation of halomethane molecules CH 2 BrI. Experimental results demonstrate excellent performance of msMS DE in searching effective femtosecond laser pulses for various tasks.

Aim: This study was designed to evaluate the effects of intrauterine transplantation of menstrual blood stem cells (MenSCs) on endometrial thickness and pregnancy outcomes in patients with refractory intrauterine adhesion (IUA). Methods: This study included a group of infertile women (n = 12, age 22-40 years), with refractory IUA. Autologous MenSCs isolated from the women's menstrual blood were expanded in vitro and transplanted into their uteruses, followed by hormone replacement therapy. Transvaginal ultrasound examination was performed to assess the endometrial thickness. Transabdominal ultrasound was conducted to detect pregnancy outcome. Results: Autologous MenSCs were successfully isolated and expanded from menstrual blood and transplanted into the uterus of each patient. A significant improvement of the endometrial thickness was observed from 3.9 ± 0.9 to 7.5 ± 0.6 mm (P < 0.001). No adverse reaction was observed. The duration of menstruation was increased from 2.4 ± 0.7 to 5.3 ± 0.6 days (P < 0.001). Five out of 12 patients achieved clinical pregnancy and the pregnancy rate was 41.7%. Conclusions: Intrauterine transplantation of autologous MenSCs results in regeneration of endometrium, a prolongation of menstrual duration and an increase rate of pregnancy in patients with refractory IUA.

signaling pathways closely related to oocyte aging, including the meiosis signaling pathways containing CDC26. q-PCR confirmed the RNAsequencing results, including decreased CDC26 mRNA and protein level in oocytes from older compared with younger women. Recombinant overexpression of CDC26 rescued meiotic defects. After 2 days in culture, 37.5% of the germinal vesicle stage oocytes injected with the CDC26 construct developed to metaphase, versus only 16.7% of controls. These results demonstrate that CDC26, a key factor in the APC/C complex, is downregulated in oocytes from older women and overexpression of CDC26 through lentivirus transfection partially rescues defective meiotic progression. Although preliminary, these studies shed light on an urgent clinical problem, and merit further investigation.-DK)