No abstract

Herbal medicinal products can contain whole or partially prepared plant components from plant leaves, bark, stems, flowers and seeds.They are administered orally, inhaled or directly applied in the skin. Ruta chalepensis is a wild herb of the Mediterranean region used by many countries in herbal medicine. The existence of bioactive molecules responsible for their pharmacological properties has been shown by phytochemical screening. Results of kidney protective activity of plant. Showed that: for total cholesterol, the effect was dose dependant (50 and 100 mg\kg) in which the plant decreased it in compared to positive and negative groups (162.1±1.83 and 154.6±1.11 mg\dl) compared to (202.1±1.13 and 167.5±2.96 mg\dl) respectively. For total protein, creatinin and albumin the plant also had the ability to keep it near control groups compared to CCL4group.While the results of interaction groups indicated the ability of plant to provide protection against CCL4 damage. the plant possessed the ability to keep testosterone, progesterone and estrogen hormones level near normal in compared to CCL4 treated group (2.96±0.03, 1.93±0.01 and 3.63±0.04 ng\dl); (11.51±4.12, 9.85±2.18 and 11.78±3.42 ng\ml); (29.07±7.21, 30.11±9.11 and 30.67±8.98 ng\ml) for 50,100 mg\kg and negative control respectively. While for interaction group the results showed the ability of plant to counteract the damaged caused by CCL4 (1.67±0.01, 2.54±0.02); (10.42±2.21, 13.65±4.37); (39.74±10.13, 35.45±9.91) for testosterone, progesterone and estrogen hormones in Ruta chalepensis +CCL4 at dose (50 +0.02%) and (100+0.02%) respectively. All results of histo-architecture for kidney and testis showed the ability of plant to counteract any necrosis and abnormality caused by CCL4.

Obesity is a leading preventable cause of death worldwide, with increasing prevalence in adults and children, Obesity is one of the most important health problems in human beings and it increases the likelihood of various diseases, such as type 2 diabetes, and particularly heart disease, systemic hypertension, hyperlipidemia, cardiovascular diseases, and certain types of cancer and osteoarthritis and authorities view it as one of the most serious public health challenges of the 21st century. The consumption of bioactive compounds from the diet or dietary supplementation is one possible way to control obesity and to prevent or reduce the risks of getting various obesity-related diseases. Recently, there has been a remarkable interest in finding natural lipid inhibitors from natural products to replace synthetic compounds. Natural substances are presumed to be safe since they occur in plant foods, and are therefore seen as more desirable than their synthetic counterparts. Salvia hispanica L., commonly known as chia, is an annual plant belonging to the Lamiaceae family. Originating in some countries, chia seed was used and consumed as a source of energy and incorporated into a number of foods in the diet of the indigenous Aztec civilization.