Nanomagnetic Fe3O4@SiO2@ZnCl2 was used as a simple, cost-effective, and reusable heterogeneous catalyst for the synthesis of 2,6-diamino-4-arylpyridine-3,5-dicarbonitriles by a one-pot-three-component condensation reaction of malononitrile, ammonium acetate, and aldehydes under solvent-free conditions at 110 °C. Simple and mild reaction conditions, facile preparation of the catalyst, the use of a cheap catalyst and easy workup and isolation are notable features of this method.
ABSTRAKNanomagnetik Fe3O4@SiO2@ZnCl2 digunakan sebagai katalis sederhana, hemat biaya, dan merupakan katalis heterogen yang dapat digunakan kembali untuk sintesis 2,6-diamino-4-arilpiridin-3,5-dikarbonitril melalui reaksi kondensasi tiga komponen one-pot antara malononitril, amonium asetat, dan aldehida dengan kondisi tanpa pelarut pada temperatur 110 °C. Kondisi reaksi yang sederhana dan ringan, persiapan katalis yang mudah, penggunaan katalis yang murah dan mudah dilakukan serta mudah diisolasi adalah aspek yang penting dari metode ini.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.