Background: We aimed to reveal how chronic diseases, age and gender affected morbidity and mortality in patients with Coronavirus disease of 2019 (COVID-19). Methods: Medical records of all reverse transcription polymerase chain reaction (RT-PCR) positive COVID-19 patients followed up in hospital and home isolation between 13th of Mar 2020 and 12th of May 2020 were retrospectively reviewed. The patients were from Kayseri Province, Turkey. Patients’ demographic and clinical characteristics and the factors associated with morbidity and mortality were analyzed. Results: Of all the patients, 773 (95.8%) were alive and 34 (4.24%) died. The fatality rate was 4.2%. There were differences between the age groups in terms of fatality rate (P<0.001). The fatality rate in patients above the age of 65 yr was significantly higher. The fatality rate in the male gender was 2.44 times higher (P<0.05). It was 1.104 times higher in advanced age (P<0.001) and 10.893 times higher in patients with at least one comorbid disease (P<0.05). Hypertension increased mortality by 3.635 times (P<0.05) and chronic pulmonary diseases by 2.926 times (P<0.05). Conclusion: Advanced age, male gender and accompanying chronic diseases have adverse effects on the course and severity of the disease and hospitalization. They also increased the rate and risk of mortality.

Objective: In this study, we aimed to evaluate central venous catheter insertion related complications and related risk factors in a pediatric intensive care unit. Material and Methods:All patients hospitalized between 17.10.2012 and 24.08.2014 in a pediatric intensive care unit were included in the study. Central venous catheterization patients in terms of age, sex, cause of catheter insertion, and removal, depending on catheter interventions, were evaluated in terms of developing complications and risk factors.Results: A total of 139 catheter insertions were performed. The success rate of catheterization was 95%, attempt complication rate was 21.6%, and catheter-related blood stream infections occurred for 16.2 catheter days per 1000 catheterization days. The median duration of the catheters in place was 14 days (1-68) days. The most common site of intervention was the femoral region (38.8%), followed by subclavian (30.9%) and jugular regions. The most common complication of attemps was arterial puncture (12.2%), followed by malposition (4.3%), pneumothorax (3.5%) and other complications (2.1%). Serious complications were most common in subclavian insertions (p<0.05). After insertion, the most common complication during follow-up was catheter-associated bloodstream infection. There were no significant differences between the regions in terms of catheter-associated bloodstream infections (p>0.05). The risk of infection increased with increased duration of hospitalization (p>0.05).Conclusion: Despite associated complications, central venous catheter placement is a safe procedure in children. We suggest preference of the femoral or internal jugular vein initially, instead of the subclavian vein, because of fewer serious insertion-related complications. (Yoğun Bakım Derg 2016; 7: 9-14) Keywords: Children, complication, central venous catheterization, critical care Bulgular: Toplam 139 kateter girişimi yapıldı. Kateterizasyon başarı oranı %95, girişim komplikasyonu oranı %21,6, kateter ilişkili kan akımı enfeksiyonu oranı her 1000 kateter gününe 16,2 idi. Kateter kalış günü ortanca 14 (1-68) gün idi. En sık tercih edilen girişim bölgesi femoral bölge (%38,8) idi, bunu takip eden subklavyen (% 30,9) ve juguler (%30,2) bölgeydi. En sık görülen girişim komplikasyonu arterial ponksiyon (%12,2) idi, bunu sırasıyla malpozisyon (%4,3), pnömotoraks (%3,5) ve diğer komplikasyonlar (%2,1) izlemekte idi. Ciddi komplikasyonlar daha çok subklavyen bölge girişimlerinde görüldü (p<0,05). En sık görülen izlem komplikasyonu kateter ilişkili kan akımı enfeksiyonuydu. Kateter ilişkili kan akımı enfeksiyonu açısından bölgeler arasında anlamlı fark görülmedi (p>0,05). Kateter kalış süresinin ve hastanede yatış süresinin uzaması ile enfeksiyon gelişme riskinin arttığı tespit edildi (p>0,05).Sonuç: Çocuk hastalarda santral venöz kateter uygulamasına bağlı komplikasyon gelişimi söz konusu olsa da, santral venöz kateter uygulaması güvenilir bir girişimdir. Femoral ve juguler bölgelerde girişime bağlı ciddi komplikasyonların subklavyen...

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Purpose: How the immune response of people infected with SARS-CoV-2 develops against the virus and how long it is effective is one of the most important questions during the pandemic period. We aimed to examine the frequency of relapse and re-infection, examine the influencing factors, evaluate the cases' clinical conditions and symptoms, and examine the severity of subsequent infection. Materials and Methods: This is a descriptive and cross-sectional type study using the Public Health Management System (PHMS) records of the Turkish Ministry of Health. Clinical improvement and negative RT-PCR test results, and positive RT-PCR test results at least 45 days after the first infection were included in this study. The cases were divided into two groups: the relapse group, those positive for 45-89 days after the first infection, and the reinfection group after 90 days recommended by the CDC. Demographic characteristics, whether or not to be a health worker, accompanying chronic illness, and re-positivity periods were evaluated. Results: The total number of cases was 103,096. The number of cases with repeat positivity detected after 45 days was 78. In the study, the number of cases in the relapse group (45-89 days) was 49, while the number of cases in the reinfection group (over 90 days) was 29. Conclusions: The very low rate of reinfection and milder symptoms in the second infection are promising for vaccination studies. Understanding the COVID-19 reinfection could be the key to guiding government and public health decisions in the coming months.

Objective: This investigation was performed to determine the prevalence rate of depression and its correlates in students at Erciyes University. Method: A total of 1003 university students at the Medical, Theology and Engineering Faculties of Erciyes University in Kayseri, Turkey were included in the study. A socio-demographic questionnaire and a Beck Depression Inventory were completed by the students. An unpaired t test, a one way ANOVA test and a logistic regression analysis were used for the statistical analyses. Results: Total numbers of male and female students in the study group were similar and the mean age was 20.3±1.8. The mean Back Depression Inventory Beck Depression Inventory score was 11.3±8.6 points and prevalence rate of depression (Beck Depression Inventory ≥17) was 21.2%. The Mean Beck Depression Inventory score and depression prevalence were found higher among the students who had a physical illness, who were not satisfied with their body image or their faculty and who rated the economic level of their families as poor. Conclusion: It was concluded that approximately one-fifth of the students had depression. For the students, studying in a faculty which they are not satisfied is a major factor affecting depression. A better leadership should be provided for the students during the faculty selection procedure.