The Gm(1), Gm(2), Gm(5) and Inv(1) allotypes and Gc groups among Chinese and mountain aborigines in Taiwan and Ryukyuans have been determined. In China, the cline of Gm and Gc gene frequencies has been demonstrated; the frequency of Gm1,5 allele decreases from south to north and Gm1,2 and Gc2 alleles and Inv(1) phenotypes increase from south to north. Mountain aborigines are characterized by higher frequency of Gm1,5 and lower frequency of Gc2. There is a difference between Okinawa and Miyako islanders in the frequencies of Gm alleles.
The human biliverdin-IX β reductase gene (BLVRB) has been newly isolated from a human liver cDNA library. We now report the chromosome mapping of this gene by fluorescence in situ hybridization, using a 0.76-kb cDNA fragment as a probe. The BLVRB gene was localized to chromosome region 19q13.13→q13.2.
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