The effect of beta-adrenergic antagonists on ET-1 production of the endothelium may at least partially explain the efficacy of beta-blockers in the treatment of diseases such as advanced heart failure, essential hypertension as well as acute coronary syndromes.
Objective: Discussing whether occurs reperfusion malignant ventricular arrhythmia by intravenous injecting metoprolol before the intervention treatment of Left Anterior Descending (LAD) of Acute Myocardial Infarction (AMI) and observing the change of heart rate.
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