possible case of diabetes for the first time plasma glucose values ought to be reported. If anticoagulants interfere with the precipitating second antibody of double antibody insulin assay systems then separation of insulin ought to be achieved by other methods-for example, by adsorption to charcoal. They are equally efficient and simple to use.Glucose and insulin responses are being studied under widely varying circumstances-relation between mother and fetus, hypoglycaemic disturbances in the neonate, and the effects of new oral hypoglycaemic agents. Precise comparisons of data in these and other fields cannot be made unless glucose and insulin concentrations are determined on the same basis. An agreement on basic methodology will help to save a great deal of confusion in the future.
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