Freeman (1935) was the first to measure directly the effect of local temperature on blood flow in an extremity. He obtained figures for volume blood flow in the hand at local temperatures from 18 to 410 C and found that the curve for blood flow against temperature was similar to that described by Lewis (1929) for the effect of temperature on digital pulse volume. In the forearm Barcroft & Edholm (1943) established figures for blood flow using water-baths at different temperatures, and later (1946) extended these to the forearm in air.In the normal foot the resting blood flow has been measured at one or two local temperatures by various workers
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