Fourteen trials were conducted to evaluate the effects of feeding monensin at 33 ppm alone, tylosin at 11 ppm alone and the two feed additives in combination on the average daily gain, average daily feed intake, feed:gain ratio and the incidence of liver abscesses in feedlot cattle. Monensin reduced feed intake and improved feed efficiency (P less than .05), and had no effect on average daily gain. Tylosin improved average daily gain (P less than .05) and had no effect on daily feed intake. The effect of tylosin on feed efficiency approached significance. The interaction of monensin and tylosin was nonsignificant for daily gain, daily feed intake and feed:gain ratio. Monensin had no effect on liver abscess incidence, while tylosin reduced abscess incidence from 27 to 9%.
Two series of trials were conducted to evaluate alternative methods of administering monensin to pasture cattle. In a series of five trials, monensin was incorporated into supplements at 440 mg/kg to provide an average intake of 200 mg X head-1 X d-1 for growing cattle on pasture. Comparisons were made between daily and alternate-day feeding of the supplements. A control treatment consisting of unmedicated supplement fed daily also was included. Monensin at 200 mg/d and 400 mg on alternate days increased gain by .077 (P less than .01) and .082 (P less than .01) kg/d above control-cattle gains (.54 kg daily). Nine pasture trials were conducted to compare the effectiveness of monensin in increasing the daily gain of growing cattle when hand-fed daily in a supplement or self-fed in supplements that contained salt to regulate supplement intake. Desired supplement intakes were approximately .454 kg X head-1 X d-1 in six trials, .68 kg/d in one trial and 1.81 kg/d in two trials. Monensin produced gain increases of .09 kg daily (P less than .01) with both feeding systems. The daily gains of cattle that were hand-fed and self-fed were equal (P greater than .10). Self-fed treatments containing monensin required fewer changes in salt level than self-fed treatments not containing monensin, and the salt levels required to limit intake were generally 25 to 50% lower when monensin was in the supplement.
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