Background: To compare the effect of cyclopentolate versus tropicamide eye drops on anterior surface corneal parameters using Keratograph 4 in myopic and emmetropic individuals.Methods: Fifty-eight participants included 29 emmetropic and 29 myopic individuals, were recruited, according to inclusion and exclusion criteria. At baseline visit, anterior surface corneal parameters were measured using Keratograph 4 Keratograph 4in the right eye. All measurements were repeated at two separate visits, one week apart, after administration of tropicamide 1% and cyclopentolate 1% at similar conditions.Results: Of 58 participants who completed the study, 29 (24 women, 5 men, age: 23.82± 2.78 years) were emmetropic and 29 (21women, 8 men, age: 23.66± 2.76 years) were myopic. Baseline mean spherical equivalents were -0.23±0.23 D and -2.45±1.03 D in emmetropic and myopic groups, respectively. The analysis of the data showed a significant hyperopic shift following instillation of both cycloplegic eye drops in both refractive groups. However, tropicamide results was statistically insignificant in comparison with cyclopentolate (p=0.49). The assessment of data revealed no statistically significant differences in anterior surface corneal parameters in baseline, tropicamide and cyclopentolate instillation in each refractive group, except IHD value with tropicamide in myopic group (p=0.02). The further analysis between refractive groups also showed no significant differences in anterior surface corneal parameters in each session.Conclusions: Present study indicates that cyclopentolate and tropicamide do not appear to affect corneal topographic parameters and hence can be trusted to capture topography data.
PurposeCorneal topography is a non‐invasive medical imaging technique for mapping the surface of the cornea. Since cornea is normally responsible for more than 70% of eye refractive power, its topography is of great importance in determining the quality of vision and corneal health. It seems important to have detailed information of corneal topography in order to understand contribution the cornea makes to vision.Methods500 eyes of 500 normal subjects were investigated using the Oculus Corneal Topographer. Slit lap biomicroscopy was utilized in conjunction with standard descriptions of changes to assess pathologies of anterior segment. Anterior surface of the cornea and lid angle were evaluated using Oculus Corneal topographer.ResultsThe average corneal power in steepest and flattest meridian were 44.28 ± 1.51 and 43.44 ± 1.47, respectively. The mean of corneal astigmatism was −0.90 ± 0.55 diopters. The average value of corneal parameters were as follow: Eccentricity 0.52±0.11, Index of Surface Variation 18.73 ± 5.36, Index of Vertical Asymmetry 0.12 ± 0.05, Keratoconus Index 1.01 ± 0.02, Central Keratoconus Index 1.01 ± 0.01, Index of Height Asymmetry 6.21 ± 4.21 and Index of Height Decentration 0.01 ± 0.00. The mean of pupil diameter was 3.43 ± 0.72. Corneal asphericity was estimated in three diameters of 5, 6 and 7 mm and the average values were −0.21 ± 0.11, −0.24 ± 0.10 and −0.27 ± 0.11, respectively. The mean value of lid angle was reported as 12.29 ± 3.77 degrees.ConclusionsThis study have provided detailed and applicable description of computerized corneal topography parameters in a normal population which is useful in diagnosis and management of anterior segment disorders, such as keratoconus and corneal ectatic, preoperative assessments of refractive surgery procedures and contact lenses prescription.
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