CORRESPONDENCEWe report a rare case of panophthalmitis in dengue fever. A 6 year old girl presented with 5 days fever and rash on the lower extremities, flushed face and myalgia. Examination revealed fever of 38ºC, erythematous rash, and flushed face. Investigations revealed leucopenia and thrombocytopenia. Dengue serology was positive (both IgM and IgG). Ultrasound showed ascitis and right pleural effusion. Next morning, she complained of severe pain in the left eye. On examination, right eye was normal. Vision in the left eye was 6/18. Fundus examination revealed focal leaks of exudates from venous ends of retinal vessels at superior quadrant. By evening, the left eye was swollen, with intolerable pain and vomiting. Examination revealed shallow anterior chamber, intense ciliary congestion, cloudy cornea; percluding evaluation of underlying details. Vision was reduced to perception of light. Intraocular pressure was increased. A diagnosis of acute angle-closure glaucoma was suspected and was treated accordingly. By next morning, there was gross loss of vision, proptosis and corneal clouding. Anterior chamber showed organized disc of exudates. Panophthalmitis was suspected and ultrasound was done which revealed thickening of choroid, sclera and exudation of vitreous. MRI confirmed the diagnosis and showed diffuse inflammatory thickening of the left ocular coats with hazy vitreous, peri-ocular extensions of the inflammatory process involving both pre and post septal soft tissues, retro-orbital fat and peri-optic neural sheath showed inflammatory changes.Ocular manifestations in dengue, though rare, are not uncommon, with 20% having ocular pain [1] and 40.3% having subconjunctival hemorrhage, dilatation and tortuosity of retinal vessels and hard exudates [2]. Chorioretinitis, retinitis, retinal vasculitis and optic nerve involvement have been found to be associated with dengue [3]. Anti-IgM dengue antibody was found to be positive in 18% of patients with multifocal retinitis [4]. The triad of eye flashes, floaters and blurring of vision was highly predictive for the development of retinal hemorrhages [5]. The pathogenesis of panophthalmitis is not known. It could be the part of immunologic and inflammatory response to the dengue virus infection. The child recovered, with visual loss of left eye.Ocular manifestations in dengue are rare, but can be as serious as panophthalmitis in this child. So a systematic ophthalmic examination in patients with dengue fever, especially with ocular symptoms, is mandatory.
Purpose: To study the effect of the topical Non-Steroidal Anti Inflammatory Drug (NSAID), Flurbiprofen 0.03%, as an alternative to the topical steroids for the postoperative control of inflammation in cataract surgeries. Methods:The effect of the topical NSAID, flurbiprofen sodium 0.03%, was studied and compared with that of the topical steroid -Loteprednol etabonate 0.5% suspension (as eye drops) in a prospective, open labelled study. Both the groups (20 patients each) were similar in the baseline parameters. The postoperative inflammatory response following the standard, small incision, extra capsular cataract extraction was assessed in both the groups for 28 post-operative days. The parameters which were considered for the study were conjunctival hyperaemia, ciliary congestion, corneal oedema, cells in the anterior chamber, aqueous flare and ocular pain. The severity of the postoperative inflammatory responses for both the drugs was graded on the post-operative days 1, 7, 14, 21 and 28 and it was statistically analyzed. Results:The 2 groups did not differ statistically in the effect of the treatment for any of the variables, which included aqueous cells, flare, ciliary congestion and conjunctival congestion (p< 0.001). Both the drugs were well tolerated and no severe adverse Drug Reactions (ADRs) were caused by the topical NSAID and the topical steroid. Conclusion:The topical NSAID, Flurbiprofen, is as effective as the topical corticosteroid, Loteprednol and it can be used as an alternative in the routine postoperative treatment following uncomplicated cataract surgeries.
To study safety and benefits of bilateral cataract surgery in a tertiary care ophthalmic centre of multi-specialty hospital in bilateral cataract cases DESIGN: Prospective study. MATERIALS AND METHODS: Prospective study done during May 2011 to Feb. 2012. A total 166 subjects underwent Bilateral Small Incision Cataract Surgery (SICS). Out of 166 subjects 83 subjects underwent Immediate Simultaneous Sequential Bilateral Cataract Surgery (ISBCS) in the same sitting, 83 subjects underwent bilateral cataract surgery at the interval of 48 hours Delayed simultaneous bilateral cataract surgery (DSBCS). RESULTS: All had uneventful convalescence, single hospital admission and simultaneous Bilateral Visual recovery. CONCLUSION: No case had post-operative sight threatening infections. Subjective motivation for ISBCS better than DSBCS as it was single OT visit and one time surgery KEYWORDS: Bilateral, simultaneous, immediate simultaneous bilateral cataract surgery. Delayed simultaneous bilateral cataract surgery. INTRODUCTION: Globally, the number of people of all ages visually impaired is estimated to be 285 million, of whom 39 million are blind. People 50 years and older represent 65% and 82% of visually impaired and blind, respectively. The major causes of visual impairment are uncorrected refractive errors (43%) followed by cataract (33%). 1. Blindness due to cataract often bilateral presents an enormous problem in India not only in terms of human morbidity but also in terms of economic loss and social burden. The main causes of blindness in India are as follows:-Cataract (62.60%) Refractive Error (19.70%) Corneal Blindness (0.90%), Glaucoma
The aim of this study is to determine the frequency of positive serology among patients who underwent elective cataract surgery. METHODS: Retrospective study of 800 cases who underwent thorough laboratory work up as a part of clinical study. 490 were male (61.25%) and 310(38.75%) were female. 35 cases (4.37%) were positive for serology. Hepatitis A in 9(1.13%) cases , Hepatitis B in 6 (0.75%)cases ,hepatitis C in 10 (1.3%)cases ,HIV positive in 8 (1%)cases , VDRL in 2 (0.25%)cases. All cases were grouped as high risk cases for Operating theatre (OT) supportive staffs and surgeons and operated with extra caution. RESULTS: Retrospective analysis of incidence of positive serology in camp cases were found significant. All were operated with all safety measures to protect surgeons and other supportive staffs. CONCLUSIONS: Study proves that serological work up is necessary for all the cases posted for elective cataract surgery. Serology positive patients need special attention to safe guard the surgeon and other supportive staffs KEYWORDS: Elective Cataract surgery, serology, Non manifest sero positive cases, professional health hazard, protective measures. INTRODUCTION: Cataract is a preventable cause of blindness and cataract surgery is the most common surgery performed worldwide to restore vision. As per NPCB2011 (National Program for Control of Blindness), 1% of the Indian population (121 core) is blind. Of this, 62% are blind due to cataract. Incidence of cataract is 0.4% to 0.5%. Approximately 7 million people
The drugs currently available for treatment of glaucoma are â-blockers, sympathomimetics, carbonic anhydrase inhibitors (CAIs) and prostaglandin analogues 1 . Apart from their use in glaucoma to reduce IOP, the antiglaucoma drugs are also used routinely for pre-operative reduction of IOP even in nonglaucomatous patients subjected for intraocular surgery to prevent expulsive haemorrhage and bulging of anterior segment. Objectives: To assess the safety and tolerability of 2% dorzolamide and 0.5% timolol maleate in Pre-operative Cataract patients. Materials and Methods: A prospective, comparative study enrolling 60 Pre-operative Cataract patients (30 in each group) attending Ophthalmology inpatient department in Kempe Gowda Institute of Medical Science Hospital and Research Centre. Dorzolamide was instilled thrice daily and timolol maleate twice daily for 2 days. IOP was measured on zero, 2 nd , 24 th and 48 th hours and also looked for side effects. Results: The mean reduction of IOP was 17.1% with dorzolamide and 18.9% with timolol maleate. Both the drugs were tolerated very well without any systemic adverse effect and the local side effects were comparatively less with dorzolamide. Conclusion: Efficacy of dorzolamide in decreasing IOP in Pre-operative Cataract patients was almost comparable to timolol, and dorzolamide appeared to be relatively better tolerated.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.