Antibacterial activities of the root extract and pre-formulated cream were evaluated by Kirby-Bauer Disk Diffusion Method against three microorganisms, namely, Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa. Likewise, the pre-formulated cream was evaluated for its anti-inflammatory activity using mice injected with 0.1 mL of 1% carrageenan solution to induce inflammation. The degree of inflammation was measured using a digital Vernier caliper at 0, 1, 2, and 3 hours after the stimulus was made.Evaluation results showed that the pre-formulated 2% root extract cream of the plant possess anti-inflammatory activity rather than antibacterial activity.
IndexTerms-Antibacterial, anti-inflammatory, Kirby-Bauer disk diffusion method, S. spontaneum Linn. cream.
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