Background Fever of unknown origin (FUO) is a challenging clinical problem in medicine that needs collaboration of various diagnostic techniques to establish the accurate diagnosis. We evaluated the diagnostic performance of 18F-FDG PET/CT in patients who presented themselves with FUO. Our study included 40 patients with FUO who underwent PET/CT examination and their results were compared to the results of laboratory, histopathological, microbiological investigations and/or response to therapy. Results The final diagnosis included malignancy in 20 patients (50%), infectious causes in 7 patients (17.5%) and non-infectious inflammatory causes in 6 patients (15%). Fever resolved without diagnosis in 4 patients (10%), while no definite diagnosis was reached in 3 patients (7%). PET/CT successfully contributed to diagnosis of 35 out of 40 patients with diagnostic accuracy of 87.5%. The sensitivity, specificity, positive predictive value and negative predictive value of PET/CT in our study were 93.5%, 66.7%, 90.6% and 75%, respectively. Conclusion PET/CT is a useful tool to investigate and diagnose the cause of FUO. It provides information that can guide the treatment strategy of the patients.

Background: multidetector row computed tomography (MDCT) provides reliable diagnostic information on the normal anatomy of the aorta, pulmonary arteries & veins and vena cava, as well as congenital anomalies in pediatric and adult patients. Objective: in this study, we assess the role of multidetector CT scan in the evaluation and its ability to diagnose congenital thoracic vascular anomalies as well as it is importance to recognize these anomalies early for proper treatment and follow up, and also to prevent morbidities and mortalities. Patients and Methods: the study was done in National Heart Institute, Ministry of health Egypt. It included a total of 80 patients (50 males and 30 females, their age ranged between, 2 days to 64 years and the mean age was 11.6±18 years), who underwent MDCT (using GE 16/64-multislice CT) angiography from December 2018 to June 2019 and had diagnosed of congenital thoracic vascular anomalies, or asymptomatic (incidentally discovered). Results: a total of 80 patients had done 16/64-MDCT angiograms were considered to be of adequate diagnostic image quality. Twenty-seven patients diagnosed as systemic arterial (aortic) anomalies corresponding to 33.7% in all cases, the right aortic arch anomalies (9 cases) are represented the most frequent cases (11.2 %). Conclusion: The ability to diagnose congenital vascular thoracic anomalies has evolved tremendously in the past 20 years. Traditional methods of plain radiographs and barium swallow studies as well as invasive angiography have now been supplanted with MR imaging and MDCT, minimally invasive methods that provide superb resolution and a large field of view.

Background Fibroadenomas (FAD) are benign tumors composed of stromal and epithelial elements. These tumors are commonly seen in young women. Multiple or complex fibroadenomas may indicate a slightly increased risk for breast cancer. Aim of the Work To assess the diagnostic accuracy of ultrasound in atypical fibroadenoma. Materials and Methods This retrospective study was approved by Ain Shams radiology department. On the basis of results of core needle or excisional surgical biopsy, we retrospectively identified 40 consecutive patients between October 2017 and October 2018 with the diagnosis of fibroadenoma. Results In our study, we found that The mean age in the simple fibroadenoma group was 29 years (range 18-49), and in the complex fibroadenoma group, it was 38 years (range 17-62) which represents statistically significant difference between the two groups (P =.021). Conclusion Complex fibroadenomas showed some characteristics that could help in differentiating them from their simple counterparts, namely, an irregular shape, noncircumscribed contours, a complex echo structure. The awareness of these distinguishing features could help radiologists decide which fibroadenomas should be sampled.