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K E Y W O R D S : dermatopathology, lymphadenectomy, malignant PEComa, perivascular epithelioid cell, S100We report a metastasizing PEComa in a pregnant 41-year-old female who had initially presented at her dermatologist's during the first trimester of pregnancy with a newly developed indolent, slowly grow-

From 2004 to 2007 10 cases (7 women, 3 men) of granular parakeratosis were found corresponding to a frequency of 0.004%. The average age was 62 (33-82). In women lesions occurred in submammary region (4), axillae (2) and popliteal fossa; in men, groin (2) and genital region. Clinically two different patterns are recognized--lichen planus-like red-brown slightly hyperkeratotic or scaly papules, and larger plaques which are either bright red shiny or grey-brown with lichenification. Histologically the typical granular parakeratosis was seen in a prominently thickened stratum corneum. It remains unclear whether granular parakeratosis is a disease entity or whether it reflects a reaction pattern to unknown stimuli.