A case is reported in which progressive liver symptoms with rise in bilirubin concentration, hemorrhagic diathesis, and signs of portal hypertension developed three years before death in liver coma. The pathologic and neuropathologic findings are described. The case was clarified after dimethylnitrosamine was demonstrated in food intended for the patient and after it was established that small amounts of nitrosamine could have been repeatedly ingested by the patient over a period of years. Comparable cases of human dimethylnitrosamine poisonings published in the literature are presented. The relatively typical morphologic alterations in the liver are described. Problems involved in the histological interpretation of such liver changes as well as the forensic conclusions to be drawn are discussed.
The Lower Leg F r a c t u r e of Pedestrian Victims --Possibilities and Limits of Reconstruction of Traffic Accidents Summary. The possibilities and limits of the reconstruction of pedestrian accidents by the lower leg fracture are discussed by means of clinical reports. It could be shown that the evaluation of X-ray examinations is very important. Suggestions for a optimal utilization of autopsy findings are given.Zusammen/assung. An Hand eines klinisehen Untersuchungsmaterials werden die MSglichkeiten und Grenzen der Unfallrekonstruktion aus der Form der Unterschenkelfrakturen verletzter Fugg~inger erSrtert. Hierbei hat sich die Auswertung von rSntgenologischen Befunden als wertvoll erwiesen. Es werden Vorschliige ffir eine optimale Ausnutzung der durch die Obduktion zu erhaltenden Informationen gemacht.
Proteolytic changes in the muscles of cadaver are demonstrable by putrefaction experiment with the electrofocusing on polyacrylamide gels. These changes can--within a narrow limit--be used in the determination of time of death at a stage when the early signs of death are not suitable any more. A fraction with a pI-value of 7.2 appears as a proteolytic fission at 30 degrees C not earlier than the second day after death. This fraction can be detected at 20 degrees C from the fifth to the sixth day p.m. At 10 degrees C it will not be detectable until the ninth day p.m. At a pH-range between 6.9 and 7.7, at 30 degrees C and 8 days after death, or at 20 degrees C and 9 days after death, only a relatively stable fraction is detectable with a pI-value between 6.9 and 7.0.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.