Human ferritin homopolymers with H or L subunits ͑rHF and rLF͒ were genetically engineered in E coli. Apoferritins were then reconstituted with 2000 Fe atoms. A big difference was observed in the rates of iron uptake, whereas the mean core size was similar in rHF and rLF. Magnetization of the recombinant human ferritins were measured as functions of temperature and field. The blocking temperature T B ͑H͒ at low fields is considerably higher in rLF than in rHF. From the fit of M͑H͒ data to a modified Langevin function: M͑H͒ = M 0 L͑ p H / k B T͒ + a H, the effective magnetic moment p is found to be much larger in rLF than in rHF. Experimental data demonstrate that the magnetic properties, in particular, the uncompensated spins of ferritin core are related to the biomineralization process in ferritins.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.