Abstract. Immune globulins prepared from placentas, venous plasma and mixtures of the two sources were assayed by hemagglutination inhibition for blood group substances A and B. The maximum amount of B substance in placental immune serum globulin (human) was 200 μg/ml; in venous immune serum globulin (human), 5 μg/ml; in immune serum globulin (human) from mixed sources, 27 μg/ml. The amount of blood group substance A was approximately 10% of the amount of B substance in placental globulins. Tetanus immune globulin (human) derived from venous plasma contained levels of blood group substance similar to those in immune serum globulin (human) from mixed sources.
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