Für die chirurgische Therapie ist die intravasale Ungerinnbarkeit des Blutes zur Aufrechterhaltung einer geordneten Kreislauffunktion ebenso notwendig wie eine normale Blutgerinnung bei Austritt von Blut aus dem Gefäßsystem.Schon im Jahre 200 verzichtete daher der Rabbi Gamaliel auf die Zirkumzision am erstgeborenen Sohn der jüngsten von drei Schwestern, da die Söhne der beiden älteren Schwestern daran verblutet waren. Darüber hinaus erließ er eine entsprechende prophylaktische Verordnung, die als Gesetz in den Talmund aufgenommen wurde.Diese zurückhaltende Einstellung blieb nahezu bis in die zweite Hälfte des 20. Jahrhunderts hinein vorherrschend (9,13, 18, 23).
Among 333 patients followed-up after surgery involving a heart-lung machine between 1975 and 1976 seven (2.1%) fell ill with hepatitis. Only in two of them (0.6%) hepatitis B had occurred, caused by HBs-antigen positive blood which had had to be given for a vital indication without testing beforehand. This low rate of disease must now be considered preventable, as in 1975, the time of the transfusions, blood donor control had not reached present-day perfection due to the short period of use of radioimmuno-assay (RIA). In two patients (0.6%) non-B hepatitis following transfusion cannot be excluded although in one patient use of PPSB may be responsible for the disease. Among the 3 other hepatitis cases no aetiological connection between hepatitis and transfusion could be established on the grounds of the incubation period.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.