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Optical properties of Nd3+ -doped phosphate glasses have been studied on the basis of the Judd-Ofelt theory. With the intermediate cross-section value and the weak 4 / 6 parameter, we expect a relatively prominent 4 F3/2 4 I11/2 laser emission. The quenching effect of the emission intensity is discussed in terms of cross-relaxation between the Nd3+ ions as well as energy transfer processes within the host matrix. From the investigation of the decay rate from the 4 F3/2 state with the neodymium concentration, we suggest that self-quenching is insured by dipole-dipole interaction. This result was also confirmed by the simulation of the decay with the Inokuti-Hyrayama model.

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Modifying the electrical properties of fibroblasts against various glucose concentrations can serve as a basis for a new, original sensing device. The aim of the present study is to test a new biosensor based on impedancemetry measurement using eukaryote cells. Fibroblast cells were grown on a small optically transparent indium tin oxide semiconductor electrode. Electrochemical impedance spectroscopy (EIS) was used to measure the effect of D-glucose on the electrical properties of fibroblast cells. Further analyses of the EIS results were performed using equivalent circuits in order to model the electrical flow through the interface. The linear calibration curve was established in the range 0-14 mM. The specification of the biosensors was verified using cytochalasin B as an inhibitor agent of the glucose transporters. The nonreactivity to sugars other than glucose was demonstrated. Such a biosensor could be applied to a more fundamental study of cell metabolism.