ABSTRAKBerdasarkan beberapa penelitian diketahui bahwa ekstrak daun sirsak dapat memperbaiki cedera sel beta pankreas. Tujuan penelitian ini adalah menganalisis adanya pengaruh pemberian ekstrak daun sirsak terhadap glukosa darah puasa (FBG)
Dietary fiber and resistant starch are known to be beneficial in lowering both glucose and lipid concentration in human. Fibercreme, a fiber rich product has been developed. It is a commercial non-dairy creamer that uses various oligosaccharides such as Isomaltose-oligosaccharides (IMO) or inulin as fiber source to replace the glucose component of conventional creamer. In this study, IMO and fibercreme were used to replace sucrose of the banana porridge. Therefore, the purpose of this study was to determine porridge effects on glucose, triglyceride, serum cholesterol and digesta profile in diabetic STZ-NA induced rats. Twenty-five male Wistar rats were divided into five groups and fed four different diets including the standard (KS and KN), banana porridge with sweetener IMO (BP+IMO), fibercreme (BP+FC) and (BP + Sukrosa). In these diets, porridge subtituted 30% energy of the standard diet, and the intervention was conducted for 28 days. It was found that banana-IMO porridge showed the lowest decrease in serum glucose level with 56.09%, followed by banana-fibercreme (47.61%) and bananasucrose (36.61%). Furthermore, similar trend was found in their cholesterol-lowering effects with 36.82%, 25.68% and 7.86% respectively. However, triglyceride level effects were highest in banana-IMO porridge (9.06%), followed by banana-sucrose (6.47%) and banana-fibercreme (3.72%). In addition, sucrose replacement with IMO increases weight and water content, as well as decrease caecal digesta pH. However, fibercreme increases only water content and does not decrease caecal digesta pH.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.