Glioblastoma (GBM) is one of the deadliest cancers, with limited effective treatments and single-digit five-year survival [1][2][3][4][5][6][7] Comparative cancer genomics showed that the mutation frequencies across all genes tested in mice significantly correlate with those in human from two independent patient cohorts. Co-mutation analysis identified frequently co-occurring driver combinations, which were validated using AAV minipools, such peer-reviewed)
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