Four phenothiazine derivatives are here shown to affect physiological activity in Tribolium confusum. The derivatives are proclorperazine, chlorpromazine, thioproperazine, and levomepromazine.All four have some degree of influence on adult life and egg-laying but induce no significant alteration in numbers of eggs hatched per individual.The nature of the derivatives together with their concentrations are responsible for the variations induced in rate of oviposition. Continuous feeding of the substances has a cumulative effect; the number of eggs per adult decreases gradually.The degree of toxicity to adults is also different for each derivative, the most noxious of the four substances being proclorperazine.
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