Residues in allelic positions, in the local segment of aligned sequences of proteins show wide variations. Here, we describe PROPAB
that computes the propensity tables for helix, strand and coil types from multiple 3D structure files following ab initio statistical
procedure. It also classifies them in range specific and chain specific manners. It further computes percentage composition and
physicochemical properties along with residues propensities. It also prepares FASTA files for different segments (helix, strand and
coil) in the exact order that they follow in the sequence. Representative analyses on orthologous (homologous across species) proteins
demonstrate wide segmental variations of physicochemical properties. Such variations provide insights to relate the adaptation of
these proteins in a given functional constraint under diverse environmental conditions. Thus, the program finds applications in the
structural and evolutionary analysis of proteins.Availability:PROPAB is freely available at
http://sourceforge.net/projects/propab/for worldwide user.
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