Passion fruit peel is a by-product of fruit processing, accounting for about 50% of the fruit weight. Each 100 g of fresh passion fruit peel contains 87.64 g of moisture and 6.78 g of carbohydrates (Corrêa et al., 2016). These carbohydrates have multiple biological activities.Long-term intake of Passiflora edulis peel flour can improve serum and tissue antioxidant status and regulation of oxidative stress and cecal microbiota. Pectin from P. edulis has an anti-inflammatory effect, can reduce limb edema, and inhibit the release of myeloperoxidase (Silva et al., 2011). Water extracts from P. edulis peel and its derivatives can inhibit the inflammation induced by carrageenan, histamine, and substance P, and produce various proinflammatory cytokines, mediators, and enzymes in the inflammatory site (Benincá et al., 2007). Hot water extracted polysaccharides from P. edulis peel showed an anti-tumor effect in vivo without toxicity (Silva et al., 2012). Polysaccharides isolated from P. edulis peel can also effectively regulate blood glucose and lipid levels, regulate intestinal short chain fatty acids content and GLP-1R, and promote insulin secretion (da Silva et al., 2014). However, in recent years, some studies have demonstrated that the Mw of polysaccharides will limit their biological activities (Ma et al., 2018;Ofoedu et al., 2021;Zhang et al., 2014). But this seems to be improved by Vc-H 2 O 2 degradation. Therefore, it is of great significance to study the degradation of P. edulis peel polysaccharides for its development and utilization.Based on nutrition and health awareness, people are more interested in natural organic food, additives, and drugs. Natural polysaccharide has the advantages of low toxicity and little side effects, which make it more suitable for the development and utilization of food, pharmaceuticals, and other fields. The natural polysaccharide
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