In this paper, five mathematical models of single neurons are discussed and compared. The physical meanings, derivations, and differential equations of each model are provided. Since for many applications the spiking rates of neurons are of great importance, we compare the spiking rate patterns under different sustained current inputs. Numerical stability and accuracy are also considered. The computational cost and storage requirements needed to numerically solve each of the models are also discussed.
The chiropractic clinical competency examination uses groups of items that are integrated by a common case vignette. The nature of the vignette items violates the assumption of local independence for items nested within a vignette. This study examines via simulation a new algorithmic approach for addressing the local independence violation problem using a two-level alternating directions testlet model. Parameter values for item difficulty, discrimination, test-taker ability, and test-taker secondary abilities associated with a particular testlet are generated and parameter recovery through Markov Chain Monte Carlo Bayesian methods and generalized maximum likelihood estimation methods are compared. To aid with the complex computational efforts, the novel so-called TensorFlow platform is used. Both estimation methods provided satisfactory parameter recovery, although the Bayesian methods were found to be somewhat superior in recovering item discrimination parameters. The practical significance of the results are discussed in relation to obtaining accurate estimates of item, test, ability parameters, and measurement reliability information.
In this paper, we propose an effective framework to automatically segment hard exudates (HEs) in fundus images. Our framework is based on a coarse-to-fine strategy, as we first get a coarse result allowed of some negative samples, then eliminate the negative samples step by step. In our framework, we make the most of the multi-channel information by employing a boosted soft segmentation algorithm. Additionally, we develop a multi-scale background subtraction method to obtain the coarse segmentation result. After subtracting the optical disc (OD) region from the coarse result, the HEs are extracted by a SVM classifier. The main contributions of this paper are: (1) propose an efficient and robust framework for automatic HEs segmentation; (2) present a boosted soft segmentation algorithm to combine multi-channel information; (3) employ a double ring filter to segment and adjust the OD region. We perform our experiments on the pubic DIARETDB1 dateset, which consists of 89 fundus images. The performance of our algorithm is assessed on both lesion-based criterion and image-based criterion. Our experimental results show that the proposed algorithm is very effective and robust.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.