BackgroundMediastinal follicular dendritic cell sarcoma (FDCS) is extremely rare. Due to potential under-recognization of this disease, it happens to be misdiagnosed, especially on core needle biopsy. We report 3 cases of mediastinal FDCS and provide a literature review to improve better understanding of the tumor and to reduce misdiagnosis.MethodsThree cases of mediastinal FDCS in our clinic practice were studied, including their core needle biopsy and resected specimens, and those cases reported previously in English literature were retrieved and analyzed.ResultsThe core needle biopsy of case 1 showed a tumor reminiscent of classical Hodgkin’s lymphoma (CHL), while the resected mass was finally diagnosed with FDCS combined with hyaline-vascular Castleman’s disease. Both the biopsy and resected tissue of case 2 were constitutive of the clear epithelioid cells with marked atypia. In both cases, definitive diagnoses were not made on core needle biopsy. In case 3, there were some areas morphologically similar to CHL, and some areas contained ovoid to spindle-shaped tumor cells with fascicular pattern. The analysis of 43 cases of mediastinal FDCS showed the age of patients were from 16 to 76 years old, the male to female ratio was 1.5:1, the maximal tumor diameters were 3–17 cm. 18 cases were underwent preoperative biopsy, whereas 15 (83.3%) of which were misdiagnosed initially, often as lymphoma. 32 patients had available follow-up data, the rates of recurrence, metastasis, and mortality were 12.5, 18.8 and 28.1%, respectively. Current limited data suggested no statistical differences between adverse prognosis and gender, age, tumor size, necrosis, or different therapeutics, respectively.ConclusionsMediastinal FDCS is a rare malignancy that has yet not been fully understood and been often misdiagnosed, particularly when making a diagnosis on core needle biopsy. Increased awareness of this enigmatic tumor is crucial to avoid diagnostic pitfalls.

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In December 2015, the Beijing-Tianjin-Hebei (BTH) region experienced several episodes of heavy air pollution. Beijing municipal government therefore issued 2 red alerts on December 7 and 19, respectively, and also implemented emergency control measures to alleviate the negative effects of pollution. It is estimated that the heavy pollutions in 2 red alert periods in Beijing were due mainly to the accumulation of air pollutants from local emission sources and the transboundary transport of pollutants from surrounding areas. The collected meteorological and PM 2.5 data indicate that the severity of air pollutions were enlarged by the poor meteorological conditions along with lower mixing layer height. In this study, the WRF-CAMx modeling system was utilized not only for analyzing the contributions of PM 2.5 from different sources, but also for quantitatively assessing the effects of implementing various emergency control measures on PM 2.5 pollution control during the red alert periods. The modeling results show that local emissions were the most dominant contributors (64.8%-83.5%) among all emission sources, while the main external contributions came from the city of Baoding (3.4%-9.3%). In addition, among 5 different emission source categories, coal and traffic were the two dominant contributors to PM 2.5 concentration in urban area of Beijing. Then four pollution control scenarios were designed particularly to investigate the effectiveness of the emergency control measures, and the results show that, generally these emergency control measures have positive effects on air pollution reduction. In particular, restrictive measures of traffic volume control and industrial activity shutdown/suspension have been found as the most effective measures in comparison to other emergency control measures. It is recommended that such effective measures should be considered to implement when next time similar heavy air pollutions occur in the city of Beijing.

The measurement of PM 2.5 was conducted from 15 th August to 17 th September, 2015 in Shijiazhuang, China, covering the period of a ceremonial parade. The PM 2.5 concentrations and the major chemical components were analyzed. The concentrations of PM 2.5 was 26.5 µg m -3 during control, which were 57.0% and 51.1% lower compared to before and after control, respectively. The lowest concentrations of elements and water-soluble ions were also found during control with a decreasing tread of 31.1%-44.2%, and 57.1%-64.2%, respectively. Two typical pollution episodes characterized by significantly elevated PM 2.5 concentration were found during no control due to the combination of no emission-reduction measures and unfavorable weather conditions. The mass percentage of secondary inorganic ions was larger during no control (38.1%-40.3%), pointing to the strong contribution of atmospheric chemical processes. The NO 3 -/SO 4 2-ratios were 0.85, 0.94, and 0.85 before, during, and after control, respectively, and the elevated ratios during control indicate a greater proportion of the PM 2.5 originated from vehicle exhaust. The WRF-CMAQ modeling system was also used to assess the effectively of emission reduction measures and weather conditions. The results indicated that the PM 2.5 concentration increased by 21.6% and 32.1% if no emission-reduction measures were taken and weather conditions in 2014 were used.

Market services industries are closely related to residents’ lives, and its spatial distribution has an important impact on satisfying residents’ consumption needs and promoting economic development. In recent years, with the rapid development of urban–rural integration and the gradual implementation of a rural revitalization strategy, rural areas around metropolises have become the “frontier” of urban geographic expansion, causing the rural market services industries to specialize, commercialize, and modernize. Taking Wuhan as a case study, the spatial distribution characteristics and influencing factors of the market services industries were measured using the average nearest neighbor index, the kernel density estimate, the spatial correlation analysis, and the Geodetector method. The results are as follows. (1) The market services industries in Wuhan’s new urban districts, as a whole and individually, showed characteristics of agglomeration. The market services industries overall formed two high-density areas and multiple agglomeration areas, and the high-density areas of different types of market services industries showed characteristics of partial spatial overlap. (2) There was a significant positive spatial correlation in market services industries, as a whole and individually. Among them, the life services industry had the strongest spatial correlation, while the accommodation services industry had the weakest. (3) Market demand and traffic conditions were the core factors influencing the distribution of the market services industries in Wuhan’s new urban districts, followed by urbanization and economic levels; and tourism conditions had a lower impact. Each detector had a different impact on the spatial distribution of different market services industries, and the interaction research showed that the spatial distribution of the market services industries was the result of a combination of multiple factors. This research provides a future development direction for market service industries in rural areas.

The pollution problem caused by urban black and odorous waters has received much attention from the Chinese government. Our research aims at systematically identifying the characteristics and the influential factors of spatial differentiation of urban black and odorous waters across China. The research, based on the data of black and odorous waters from 2100 Chinese cities, was conducted with the spatial analysis tool of ArcGIS. We found that the amount of Chinese urban black and odorous waters varied in spatial distribution, which was an agglomerated type with significant agglomeration. The kernel density was characterized by independent single kernel centers with ribbon-like and sporadic distributions of subcenters. The cold and hot spots showed a gradient distribution pattern of cold in the southwest and hot in the central east. These spatial distribution characteristics could be attributed to the following core factors, total wastewater discharge, length of urban drainage pipelines, municipal solid waste collection, daily urban sewage treatment capacity, and investment in urban pollution treatment of wastewater. The findings reveal the current geospatial distribution of black and odorous waters pollution and provide reference for the Chinese government to treat the pollution from several key points. Lastly, it is suggested that the Chinese government should establish joint control, joint prevention, and joint treatment mechanisms in the black and odorous waters areas and improve the safety standards of the whole water environment, so as to promote the treatment and elimination of urban black and odorous waters.

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