The current syntheses of imines from benzylamines are often performed in organic solvents or under harsh reaction conditions. Clean oxidation of primary benzylamines to imines has been successfully achieved using H(2)O(2) in water at room temperature catalyzed by V(2)O(5). Among the 10 imine products, 5 of them precipitated from the reaction and led pure products after simple filtration. No organic solvents are needed in the whole process. The yields are good to quantitative. This represents an efficient and green procedure of the synthesis of imines. A similar green oxidation of benzylamines to aromatic aldehydes is also reported. A benzylic anion-involved mechanism is proposed based on the experiments.
A new and efficient synthesis of benzyl chlorides and methylene acetals by use of 2,4-dichloro-6-methoxy[1,3,5]triazine (MeOTCT) and dimethyl sulfoxide has been developed. Chlorides are the major products for benzyl alcohols, while methylene acetals are the major products for secondary alcohols. This procedure provides the highest yields so far for methylene acetals of steroids. A plausible mechanism is proposed on the basis of the experiments.
and Stereoselective Synthesis of syn-Aryl Glycol Monoesters from Aryl Olefins with Hydrogen Peroxide Catalyzed by RuCl 3 . -In the presence of aliphatic C-C double bonds, the aryl double bonds are selectively dioxygenated. The fact that the process proceeds generally with complete selectivity [cf. (XIII) and (XV)] can be used for the preparation of natural products. -(ZHANG, Y.; CHU, G.; CUI, X.; HAN, Z.; DOU, D.; CHEN, Y.; YU, X.; LI*, C.; Synlett 2010, 7,
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