No abstract

A novel and simple methodology for the asymmetric allylation of aldehydes was reported. Double small organic molecules such as l-proline and l-prolinol were first employed for providing a chiral environment so as to afford chiral homoallylic alcohols in high yields and moderate enantioselectivities in our protocol.

This paper presents a versatile reagent for epoxide cleavage. The allyltin tribromide could act as a novel and easily prepared allylation reagent and halide atom donor to convert epoxides to the corresponding homoallyl alcohols and halohydrins in high yields with excellent regioselectivities under mild reaction conditions, respectively. It could also act as a Lewis acid to catalyze the ring opening reactions of epoxides with alcohols.versatile reagent, allyltin tribromide, ring opening of epoxides, room temperature

A novel and simple protocol for the asymmetric allylation of aldehydes is developed.