We present an overview of the OSIRIS integral field spectrograph which was recently commissioned on the Keck II Telescope. OSIRIS works with the Keck Adaptive Optics system and utilizes an infrared transmissive lenslet array to sample a rectangular field of view at close to the Keck diffraction limit. By packing the spectra close together (2 pixel rows per spectrum) and using the Rockwell Hawaii-2 detector (wavelengths between 1 and 2.5 microns), we achieve a relatively large field of view (up to 6."4) while maintaining full broad-band spectral coverage at a resolution of 3800. Among the challenges of the instrument are: a fully cryogenic design (approximately 250 kg are brought down to 55K); four spatial scales from 0."02 to 0."10; extremely low wavefront error (approximately 25 nm of non-common path error); large all aluminum optics for the spectrograph; extremely repeatable spectral formats; and a sophisticated data reduction pipeline. OSIRIS also serves as a starting point for our design of IRIS which is a planned integral field spectrograph for the Thirty Meter Telescope.
A novel FTICR cell called the trapping ring electrode cell (TREC) has been conceived, simulated, developed, and tested. The performance of the TREC is compared to a closed cylindrical cell at different excited cyclotron radii. The TREC permits the ability to maintain coherent ion motion at larger initial excited cyclotron radii by decreasing the change in radial electric field with respect to z-axis position in the cell. This is accomplished through postexcitation modulation of the trapping potentials applied to segmented trap plates. Resolving power approaching the theoretical limit was achieved using the novel TREC technology; over 420 000 resolving power was observed on melittin [M + 4H] 4+ species when employed under modest magnetic field strength (3T) and a data acquisition duration of 13 s. A 10-fold gain in signal-to-noise ratio is demonstrated over the closed cylindrical cell optimized with common potentials on all ring electrodes. The observed frequency drift during signal acquisition over long time periods was also significantly reduced, resulting in improved resolving power.Fourier transform ion cyclotron resonance mass spectrometry 1 (FTICR-MS) provides high resolution, mass measurement accuracy, and sensitivity which makes it ideally suited for analytical application in the areas of proteomics, 2-4 metabolomics,5 petroleomics,6 ,7 and many others. FTICR-MS is the high performance end of proteomics research today, with the capability to identify proteins and protein-protein interactions based on accurate mass measurements. [8][9][10] In general, the more accurately a mass can be determined, the more confident identification can be assigned for a given protein 11,12 and the more confidently unknown peptide sequences can be determined. 13 The goal to apply mass spectrometry to ever-increasingly complex biological samples furthers the demand for increased analytical capabilities and the need for development of higher performance instrumentation.The FTICR mass spectrometer relies upon an electromagnetic ion trap or cell to confine ions during detection. 14-16 The confinement is accomplished radially (x-y dimension) by an applied magnetic field parallel to the z-axis of the ion trap and axially using DC electrical potentials applied to trapping electrodes. As an ion approaches either trap plate, it experiences a force due to the electric field, and its kinetic energy is converted to potential energy. Thus, the ion exhibits periodic motion similar to the classical harmonic oscillator. As a consequence of the method by which ions are trapped within the cell, four natural motions arise. Trapping oscillation is the motion in which the ions oscillate in the zdimension of the cell. Cyclotron motion is caused by the Lorentz force and is dependent upon the mass-to-charge ratio (m/z) (eq 1).
A novel Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer has been developed for improved biomolecule analysis. A flared metal capillary and an electrodynamic ion funnel were installed in the source region of the instrument for improved ion transmission. The transfer quadrupole is divided into 19 segments, with the capacity for independent control of DC voltage biases for each segment. Restrained ion population transfer (RIPT) is used to transfer ions from the ion accumulation region to the ICR cell. The RIPT ion guide reduces mass discrimination that occurs as a result of time-of-flight effects associated with gated trapping. Increasing the number of applied DC bias voltages from 8 to 18 increases the number of ions that are effectively trapped in the ICR cell. The RIPT ion guide with a novel voltage profile applied during ion transfer provides a 3-to 4-fold increase in the number of ions that are trapped in the ICR cell compared with gated trapping for the same ion accumulation time period. A novel ICR cell was incorporated in the instrument to reduce radial electric field variation for ions with different z-axis oscillation amplitudes. With the ICR cell, called trapping ring electrode cell (TREC), we can tailor the shape of the trapping electric fields to reduce dephasing of coherent cyclotron motion of an excited ion packet. With TREC, nearly an order of magnitude increase in sensitivity is observed. The performance of the instrument with the combination of RIPT, TREC, flared inlet, and ion funnel is presented. (J Am Soc Mass Spectrom 2009, 20, 755-762)
The emission times of laser-triggered electrons from a sharp tungsten tip are directly characterized under ultrafast, near-infrared laser excitation at Keldysh parameters of 6.6<γ<19.1. Emission delays up to 10 fs are observed, which are inferred from the energy gain of photoelectrons emitted into a synchronously driven microwave cavity. Few femtosecond timing resolution is achieved in a configuration capable of measuring timing shifts up to 55 ps. The technique can also be used to measure the microwave phase inside the cavity with a precision below 70 fs upon the energy resolved detection of a single electron.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.