Multiple-Drug Resistance (MDR) is a mechanism that renders the
ineffectiveness of one or more than one antimicrobial agents shown by disease causing
microorganisms. MDR has become one of the major public health challenges as
initially, the MDR species were restricted only to hospitals, but now they are found
everywhere. Due to the slow advancements in the discovery of new or different
antibiotics against the MDR organisms, the medical society is facing great challenges
in the treatment of infections caused by resistant microorganisms. This chapter outlines
the challenges involved in drug discovery, and treatment to fight and prevent MDR
infections.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.