In the context of the COVID-19 pandemic, healthcare is faced with several new problems, one of which is a post-covid syndrome. Symptoms in many COVID-19 survivors can persist for a long time, significantly affecting the quality of life and work performance. All of the above makes post-covid syndrome a socially significant disease, requires dynamic follow-up of such patients, and rehabilitation programs development. We are currently at the stage of accumulating knowledge about the SARS-CoV-2 pathophysiology and morphogenesis and its long-term consequences. This article discusses neuropsychiatric aspects of the post-covid syndrome: pathogenetic hypotheses, clinical features, and potentially promising treatment strategies.
Aim. To investigate the effect of post-stroke epilepsy on the early recovery period of stroke.
Materials and methods. A total of 265 patients with ischemic stroke experienced epileptic seizures were under integral medical supervision. Three months after the onset of stroke 52.5% of patients had no seizures (of which in 31% post-stroke epilepsy did not develop, in 21.5% seizures were controlled by antiepileptic drugs). In 47.5% of patients, epileptic seizures continued to develop. Hospital Anxiety and Depression Scale, modified Rankin Scale, Montreal Cognitive Assessment (MoCA) test and health status questionnaire SF-36 were applied in 180 patients (90 with and 90 without seizures) two months after the stroke onset in a case-control design.
Results. A significant predominance of an increased level of anxiety and depression, number of patients with signs of disability, the average SF-36 questionnaire lower scores for general health, vitality, social functioning, role emotional and mental health indicators were revealed in patients experiencing seizures compared to patients without seizures.
Conclusion. Thus, the development of post-stroke epilepsy worsens the course of the early recovery period of stroke, functional outcomes and affects the rehabilitation potential and require timely adequate treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.