Turner syndrome (TS) is a genetic disorder caused by a numerical or structural aberration of the X chromosome, which is associated with a female phenotype. Concerning oral status, several studies have revealed that girls with TS have dental anomalies and periodontal problems. The aim of this study was to evaluate the effects of oral bacteria on caries prevalence and periodontal status in pediatric patients with TS. Materials and Methods: Twenty TS patients and 17 healthy girls were examined for cariological and periodontal status. The levels of mutans streptococci (MS), lactobacilli (LB), yeast and 10 different periodontal bacteria were determined by using culture and microarray techniques in children's stimulated saliva samples. Results: There was no difference in salivary flow rate and buffering capacity, decayed-missing-filled teeth, MS, LB, or yeast levels between the groups. Plaque index and gingival index levels were significantly higher in the Turner group and dft was significantly higher in the control group (p<0.05). As a result, microarray analysis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus were detected at high levels in the Turner group (p<0.05). Conclusion: Besides dental and craniofacial anomalies, clinicians should be alert to the early diagnosis and treatment of periodontal problems in patients with TS.

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ÖzetTurner sendromu(TS) dişi fenotipi ile ilişkili bir seks kromozom bozukluğudur. X kromozomonun tamamının ya da bir kısmının kaybı kraniyofasiyal dokuların biçim ve boyutunu etkilemektedir. TS hastaların ağız bulgularına ilişkin çalışmalar göstermiştir ki; derin kapanış, açık kapanış, çapraşıklık, diastema, sınıf II maloklüzyon gibi ortodontik anomaliler ve konjenital eksik ve fazla dişler, azalmış dental kuron genişliği, anormal dişler gibi dental anomaliler daha sıklıkla gözlenmektedir. TS hastalarda çürük, çekilmiş ve dolgulu diş değeri daha yüksek olmasına karşın periodontal problem daha yüksektir. TS hastalarda dentofasiyal bulgular diş hekimlerinin erken tanıya katkıda bulunabilmesi için önemlidir.

Stem cells are fundemental cells that have charecteristics of self-renewal and being divided unlimitedly, and generate tissue and organs. Dental stem cells have taken place among the postnatal stem cell sources as they are easy to get and require minimally invasive process. Multipotent stem cells in dental pulp, apical papilla, periodontal ligament, dental follicle and decidious teeth are isolated. It is determined that stem cells from human exfoliated decidious teeth differantiate to neurons, adipocytes, chondrocytes, osteoblasts and odontoblasts, and it is reported that they can be alternative stem cell source at autolog stem cell based therapy.