We sought to perform a meta-analysis to comprehensively evaluate the diagnostic accuracy of dual-source computed tomography angiography (DSCTA) in detecting coronary in-stent restenosis (CISR) when compared to invasive coronary angiography. The stent-based research studies in which DSCTA was used as diagnostic tool for CISR, as recent as of October 2017, from several reputed scientific libraries (PubMed, Embase, Scopus, The Cochrane Library, and Web of Science) were evaluated. Study inclusion, data extraction, and risk bias assessment were conducted by two researchers independently. Pooled sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under summary receiver operator characteristics (SROC) curve (AUC) were calculated to assess the diagnostic value. In addition, heterogeneity and subgroup analysis were also carried out. A total of 13 studies with a total of 894 patients and 1384 assessable stents were included. The pooled results of DSCTA diagnosing CISR were as follows: SEN 0.92 (95% confidence interval [CI] 0.87-0.96), SPE 0.91 (95% CI 0.87-0.94), PLR 9.83 (95% CI 6.93-13.94), NLR 0.09 (95% CI 0.05-0.15), DOR 114.73 (95% CI 64.12-205.28), and AUC 0.97 (95% CI 0.95-0.98), respectively. The subgroup analysis result suggested that DSTCA performed significantly better in CISR detection when the stent diameter was ≥3 mm compared with the stent diameter <3 mm: (0.98 [0.97-0.99] vs 0.82 [0.79-0.86]) with P < .05. This study revealed that DSCTA has excellent diagnostic performance for detecting CISR and may serve as an alternative for further patient evaluation with CISR, especially for stent diameter ≥3 mm.
The title compound, C27H17F7S2, a new unsymmetrical photochromic dithienylethene with an ortho‐fluorophenyl substituent, is one of the most promising candidates for photoelectronic applications, such as optical storage, photoswitches and waveguides. There are two molecules in the asymmetric unit. Both adopt a photoactive anti‐parallel conformation. For one molecule, the distance between the two reactive C atoms is 3.572 (6) Å; the dihedral angles between the central cyclopentene ring and the thiophene rings are 49.7 (2) and 45.9 (2)°, and those between the thiophene rings and the adjacent benzene rings are 8.1 (2) and 25.5 (1)°. For the other molecule, the distance between the two reactive C atoms is 3.588 (6) Å; the dihedral angles between the central cyclopentene ring and the thiophene rings are 43.7 (2) and 46.8 (2)°, and those between the thiophene rings and the adjacent benzene rings are 27.5 (1) and 11.1 (2)°.
Key indicatorsSingle-crystal X-ray study T = 295 K Mean (C-C) = 0.007 Å Disorder in main residue R factor = 0.068 wR factor = 0.143 Data-to-parameter ratio = 12.9For details of how these key indicators were automatically derived from the article, see
The technique of TSDO is effective, minimally invasive, and aesthetically optimal for early correction of midfacial hypoplasia of the growing children, and the technique of ODO can be used successfully for hypoplastic midface of the adults. The most postoperative retrusion appeared in the first 6 months, and no statistically significant retrusion occurred in growing patients.
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