Purpose:To determine the postoperative effects of radiotherapy (PORT) on the local recurrence-free survival (LRFS) and overall survival (OS) of stage III-N2 nonsmall-cell lung cancer (NSCLC). Materials and Methods: 183 patients with resected stage III-pN2 NSCLC from Hunan Cancer Hospital between 2013 and 2016 were divided into two groups for postoperative chemotherapy (POCT) (n = 105) or combination chemotherapy and radiotherapy (POCRT) (n = 78). The LRFS and OS were compared and the factors affecting local recurrence were illustrated in these two groups. The sites of failure based on the lobe of the primary tumor in two groups were described. Results: PORT leads to a strikingly lower risk for local recurrence and brought superior OS benefit. For different pN2 Subclassification, Patients with multiple-station pN2 ± pN1 disease had the worst LRFS (11 months) and single-station pN2 + multiple station pN1 disease had a relatively short LRFS (24 months) in group POCT. Short LRFS is correlated with multiple-station pN2, older age (Y > 55), patients with a high positive LN ratio > 1/3 and a poor tumor histological differentiation degree. In group POCT, the most frequent failure site occurs at the ipsilateral hilum (21.0%), the bronchial stump (20.0%), followed by LNs4R (19.0%), LNs4L (18.1%), LNs7 (15.2%), most of left-sided tumors more frequently involved the contralateral mediastinum, whereas the ipsilateral recurrences dominated for right-sided tumors, especially for LNs4R. In group POCRT, the highest failure site was the bronchial stump (11.5%), followed by LNs4L (8.97%), LNs1 (7.69%), the ipsilateral hilum (6.41%) and LNs4R (6.41%). Conclusion: PORT remarkably reduced local recurrence and improved OS in stage III-pN2 NSCLC, especially in the multiple-station pN2 group.
CorrespondenceZhi-Gang Liu, The cancer center of the fifth affiliated hospital
In power plants and other complex industrial application fields, incomprehensive design can make the system less durable. The fault of the fieldbus, in principle, comes from the physical layer, whose lay-out directly affects the fieldbus’s reliability. This article discusses from four aspects on how to improve the reliability of the physical layer of CAN bus, which include the selection of cables and connectors, the length of the bus and branch lines, the matching method of terminal resistor, and the interface circuit of hardware. Furthermore, the article presents the plan of using H-bridge type matching terminal, which aims at solving signal-reflection problems. Finally, the theory is verified through the application of intelligent electric actuator with the CAN bus.
A certain type of command and control system detecting and teaching platform is designed in order to realize clear display of the operation, implement of the capability teaching, detecting and fault diagnoses conveniently. This thesis which is a part of the program introduces the design and realization of a certain type of radio RF circuit board detecting and teaching platform. The platform consists of adapter and Teaching Software. Experiments indicate that the platform is reliable in the operation, can improve the efficiency of circuit board teaching and provide a method for circuit board detecting and fault diagnoses.
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