A novel chiral octahedral rhodium complex containing fluorine has been developed to be an excellent chiral sensor for a variety of amines including diamines, monoamines, amino alcohols and amino acids, showing well distinguishable 19F NMR signals and an accurate measurement of enantiomeric determination.

A simple chiral binuclear titanium complex ((S)-Ti2L3Na4) was first prepared and served as an excellent chiral sensor for discriminating a variety of chiral ammoniums by 1H NMR. In the presence of trifluoroacetic acid, the in-situ-generated ammoniums of varied amines can be effectively resolved by (S)-Ti2L3Na4. The different binding forces between (S)-Ti2L3Na4 and two enantiomers of analytes generate different shielding effects on two enantiomers, resulting in a split in the distinguishable chemical shift.

In this paper, a novel type of chiral bisselenourea sensor was first synthesized and used as a strong hydrogen-bonding donor for highly efficient chiral recognition of a diverse range of tertiary alcohols.