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The reflectivity map is theoretically investigated by applying the transfer matrix method in a metal-dielectric mirror structure at normal incidence. The existence of multiple optical Tamm states (OTSs) is demonstrated in this structure. It is found that an OTS is periodic resonance with the variation of the top-layer thickness of the dielectric mirror for a given wavelength. The energy for the corresponding OTS mainly depends on the thickness of the top layer. The appropriate thicknesses of metal film are proposed for the convenient observation of OTSs. This work may be useful in designing a new type of multichannel filter in optical communication systems.

Glucagon-like peptide-1 (GLP-1) secreted from enteroendocrine L-cells is a pleiotropic hormone with beneficial potential related to islet function, diet control, glucose homeostasis, inflammation relief, and cardiovascular protection. The present study aimed at investigating the effect of Polygonatum cyrtonema polysaccharide (PCP) after structural identification on GLP-1 secretion and the possible mechanism involved in the PCP-stimulated secretion of GLP-1. It was found that GLP-1 secretion was effectively promoted (p < 0.01) by PCP both in rats with oral administration for 5 weeks (13.9 ± 0.3–35.8 ± 0.3 pmol/L) and ileal administration within 2 h (13.6 ± 0.4–34.1 ± 1.1 pmol/L) and in enteroendocrine NCI-H716 cells with direct stimulation within 24 h (2.05 ± 0.3–20.7 ± 0.2 pmol/L). The sweet taste receptor T1R2/T1R3 was identified to be essential for NCI-H716 cells to directly recognize PCP. The intervention experiments showed that PCP-stimulated GLP-1 secretion was significantly depressed (p < 0.01) not only by antibodies, siRNA, and the inhibitor of T1R2/T1R3 but also by an adenylate cyclase inhibitor. These results suggest that PCP stimulates GLP-1 secretion from enteroendocrine cells possibly through activation of the T1R2/T1R3-mediated cAMP signaling pathway.

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