Metabolic changes, along with cardiovascular and hepatic factors, are associated with the development of diseases such as diabetes, dyslipidemia, and obesity. We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats. Twenty-five rats were divided into five groups: control (basal diet), a sucrose-fed group (basal diet plus 30% sucrose solution), and three other groups (S-OO, S-AOC, and S-AOS, indicating basal diet plus 30% sucrose solution plus olive oil OO, avocado oil extracted by centrifugation AOC or using solvent AOS, resp.). Glucose, total cholesterol, triglycerides, total protein, albumin, globulin, direct bilirubin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, cholinesterase, and α-amylase concentrations were determined and avocado oil effect on them was studied. In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α-amylase levels. AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors. Avocado oil consumption could be beneficial in the control of altered metabolic profile illnesses as it presents effects on hepatic function biochemical markers similar to olive oil.
Introduction. Determining the postmortem interval is usually based on macroscopic-morphological criteria (cadaveric phenomena); some other objective methods are often difficult to access in daily practice; therefore we analyze the usefulness of the histopathological examination of the skin as a supplementary method for determining the postmortem interval. Materials and methods. 23 patients and 92 skin biopsies were analyzed. All samples were taken in a maximum time of 6 h postmortem. Biopsies were classified into 4 groups according to the postmortem interval, with 23 biopsies in each group: 1 (1 to 6 h.); 2 (25 to 30 h.); 3 (49 to 54 h.); 4 (73 to 78 h); 21 histological criteria were analyzed with Fisher test and principal component analysis. Results. Skin biopsies of 23 corpses (mean age 51.6 years, 15 males and 8 females) were studied. 21 histological criteria were analyzed by Fisher test; statistical significance (p <0.001) with a reliability of 94.61% was achieved in 15 parameters. With the 15 selected parameters, a principal component analysis established that there were differences among the 4 analyzed groups. Conclusions. The skin histological changes may be used as a supplementary parameter in the forensic evaluation of the early postmortem interval.
Listing clearly the basic components of an autopsy, in the form of a checklist, will enable technical procedures to adequately address forensic medical autopsy findings in those cases where the cause of death is under study or is unclear, in situations such as a traffic accident, falls, or other traumas of various or non-specific origins. In this sense, the present investigation focus on forensic autopsy reports, based on a comparison between the current forensic medical reports carried out in La Paz-Bolivia and the forensic medical reports used internationally such as the Minnesota Protocol and the Medical Autopsy Protocol of Veracruz-Mexico. Using a qualitative approach with a descriptive investigation and a documental research methodology, we proceeded to collect reports from the judicial morgue of La Paz-Bolivia and the Forensic Investigation Service of Veracruz -Mexico. Based on this documentation, a bibliographic-analytical matrix was elaborated, from which the authors concluded that the main deficiency of the judicial morgue of La Paz-Bolivia is that it does not have a standardized Protocol to carry out the forensic medical autopsy reports. Therefore, an update of the forensic autopsy report was proposed along with a forensic medical autopsy protocol that serves as a reference to improve the professional service and therefore of the entire judicial morgue of La Paz-Bolivia in terms of clarification of a death. Keywords: Report, Update, Forensic Medical Autopsy, Protocol.
El vitíligo es una enfermedad dermatológica frecuente que afecta a alrededor del 1% de la población mundial. Aunque no es considerada una enfermedad con riesgo de morbimortalidad elevado, se ha evidenciado que puede asociarse con manifestaciones psicopatológicas diversas que pudieran ser una consecuencia de la misma. En el presente artículo se lleva a cabo una revisión de las evidencias actuales sobre la relación existente entre el vitíligo, los parámetros definitorios de calidad de vida, la presencia de trastornos afectivos y el posible vínculo con el aumento del riesgo de ideación suicida. Es claro que la identificación de los factores de riesgo es de suma utilidad para que los profesionales de la dermatología puedan detectar pacientes que deban ser manejados psicológicamente de manera concomitante.
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