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Background-We retrospectively examined the treatment efficacy and toxicity profile of intensity modulated radiotherapy (IMRT) plus concurrent weekly cisplatin chemotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck (HNSCC).

With a median follow-up of 18 months, PRDR appears to be an effective method to reirradiate large volumes of previously irradiated tissue in selected patients with locoregional chest wall, axilla, and supraclavicular recurrences.