Background: Lung cancer is the most common cancer causing deaths in men and women world-wide, responsible for over 1 million deaths annually. Although, advances in surgical techniques and combined therapies lung cancer remains a disease with a poor prognosis. Aim of the study was to evaluate the clinico-epidemiological and pathological profile in diagnosed case of lung cancer patients, presenting in the K N Chest hospital.Methods: Initial evaluation after obtaining informed consent, demography, history, clinicoradiological findings of patients and relevant investigations was recorded. Histopathological reports reviewed.Results: Our study included 108 patients with confirmed cases of lung cancer.The mean age of the patients was 57.50 years. The male:  female ratio was 5.8:1. Cough was the most common presenting symptom (77.78%) followed by chest pain (62.33%). Clubbing was most commonly associated with squamous cell carcinoma. Most common radiological presentation was consolidation (42.59%) followed by mass lesion (30.55%). Most common histopathological type of lung cancer found in this study was squamous cell carcinoma 47(43.52%) followed by adenocarcinoma 42 (38.89%). Small cell carcinoma was present in 15 (13.89%) and large cell carcinoma was present in 4 (3.70%) study group. The most common pathological cell type in silica dust exposed patient in this study was squamous cell carcinoma followed by adenocarcinoma with occupational history of > 10 years of silica dust exposure in stone mines.Conclusions: Squamous cell carcinoma still remains the commonest histological subtype followed by adenocarcinoma.

Ocular involvement can be a comorbidity of several pulmonary disorders. A knowledge of these manifestations is essential for early diagnosis and treatment. Hence, we aimed to review the common ocular manifestations of Asthma, COPD, sarcoidosis, obstructive sleep apnea and lung cancer. The ocular manifestations of bronchial asthma include allergic keratoconjunctivitis and dry eye. The inhaled corticosteroids used in the management of asthma can lead to cataract formation. COPD is associated with ocular microvascular changes due to chronic hypoxia and spill over of systemic inflammation into the eyes. However, its clinical significance is yet to be known. Ocular involvement is very common in sarcoidosis, seen in 20% of cases of pulmonary sarcoidosis. It can involve almost any anatomical structure of the eye. Studies have shown the association of obstructive sleep apnea (OSA) with floppy eye syndrome, glaucoma, nonarteritic anterior ischemic optic neuropathy, keratoconus, retinal vein occlusion and central serous retinopathy. However, though association has been established, causality remains to be proven. The effect of positive airway pressure (PAP) therapy used in the treatment of OSA on the above ocular conditions is yet to be known.  The PAP therapy can itself lead to irritation and dry eyes. Lung cancer can involve the eyes by direct invasion of nerves, ocular metastasis or as a part of paraneoplastic syndrome. The purpose of this narrative review is to raise awareness about the association between ocular and pulmonary disorders to facilitate early detection and treatment of these conditions.

Saber sheath trachea is defined as an anteroposterior (sagittal) diameter of intrathoracic trachea exceeding to lateral (coronal) by a ratio of 2:1 as measured at the site 1 cm above the aortic arch and the extra thoracic trachea being normal. It is most commonly seen in males and is considered to be a diagnostic sign of Chronic obstructive pulmonary disease.

Soft tissue tumors account for a small percentage of malignancies and synovial sarcomas account for 10% of soft tissue tumors in our body, among them are the synovial sarcomas (SS).These arise from various sites and are of mesenchymal origin, Primary pleural synovial sarcomas are very rare tumours and account for not more than 0.5% of lung malignancies, they are being diagnosed mainly by the immunohistochemistry and classical cytogentic translocation t(x;18). This tumor has no sex preference and is commonly seen in the age group of 30-45.Our case is of a elderly male with massive pleural effusion who was diagnosed as having biphasic variant of synovial sarcoma of pleura by the help of immunohistochemistry. Treatment is mainly surgical resection and chemotherapy with ifosfamide/ adriamycin or radiotherapy. It must be considered as differential for biopsy proven malignant mesothelioma and hence immunohistochemistry should be must for all biopsy proven mesotheliomas.

Pulmonary embolism remains a disease that needs high clinical suspicion to prevent mortality and morbidity. More so in young healthy individuals, the suspicion is very low as compared to old age individuals with multiple co-morbid conditions. Pulmonary embolism carries high mortality if not suspected and treatment initiated as early as possible. Authors describe a case of yellow wasp stings associated with chronic left leg DVT and pulmonary artery thrombosis, which is rare following wasp stings and therefore extend the clinical spectrum of wasp envenomation.