Although the study in general showed a moderate to good inter-observer agreement according to both ICC and Lights Kappa, still major discrepancies were identified in especially the mid-range of observations. Consequently, for now Ki67 estimation is not implemented in the DBCG treatment algorithm.
The presence of calculi in 300 whole prostates from consecutive autopsies were investigated by the Faxitron imaging technique. Calculi were found in 99% of the prostates, their number and size increasing with age. They were mainly localized in the ducts in the borderzone between the middle lobes and the periferal prostate posterolaterally, but often some were also found anteriorly in the centreline. Calculi were never seen in the middle Iobes. We found no statistically significant relation between the number, size or localization of calculi and other morphological or pathological parameters. Prostatic calculi seem to be a part of the normal process of aging, and do in only exceedingly rare cases assume any clinical importance.
A case of intrauterine fetal death with a hemangioma and pseudocysts in the umbilical cord is presented. The clinical significance of these rare lesions is not entirely clarified, but of the 20 fully documented cases of umbilical cord hemangiomas, including the present case, only nine were found with live and completely normal infants.
A case of fibrolipomatous hamartoma of the median nerve is presented. The operative findings were characteristic. The diagnosis should be confirmed by histological examination of a biopsy from an involved palmar cutaneous branch, and treatment should be limited to decompression of the ligament or fascia over the involved area.
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