Background: Wood dust is one of the most common sources of occupational exposures in the world. Objective:The aim of the present study was to assess respiratory symptoms among woodworkers of Jimma town, Ethiopia, 2018 G.C. Materials and Method:A community based comparative cross-sectional study was conducted among woodworkers and non-woodworkers in Jimma town, 2018 G.C. Multistage random sampling technique was used to select the exposed study group and convenience sampling technique was used to select the non-exposed group. A standardized structured questionnaire was used to evaluate the respiratory symptoms. A total of 140 study participants were enrolled in the study. Data were checked for completeness, entered into Epi data version 1.7 and exported to SPSS version 20 for further analysis. Descriptive statistics were computed, and results were presented with narratives, tables or figures.Results: Higher prevalence of respiratory symptoms was observed among woodworkers than non-woodworkers. The prevalence of respiratory symptoms like cough (41.4% vs. 10%), phlegm (34.3% vs.14.3%) and chest pain (32.9 vs. 17.1) shows statistically significance differences among exposed to non-exposed groups respectively Conclusion and Recommendation: The higher prevalence of respiratory symptoms among woodworkers needs due emphasis on preventive measures and awareness creation about wood dust-related respiratory symptoms.