Objectives: There are several instruments to assess health-related quality of life (HRQoL) in chronic rhinosinusitis (CRS). Unfortunately, none of them evaluates all three health domains (physical, social and psychological) important to assess the overall well-being of the patient. The Endoscopic Endonasal Sinus and Skull Base Surgery Questionnaire (EES-Q) does assess all these elements. Initially, the EES-Q is validated to evaluate the impact of endoscopic endonasal surgery (EES) on HRQoL. The aim of this study is to assess whether EES-Q outcomes differ in patients with CRS compared with healthy individuals. Therefore, extending the use of the EES-Q for all CRS patients.
Objective: Social functioning is an important factor in the evaluation of postoperative health-related quality of life (HRQoL) for pituitary adenoma patients. In a prospective cohort study multidimensional HRQoL of non-functioning (NFA) and functioning (FA) pituitary adenoma patients were evaluated following endoscopic endonasal surgery using the endoscopic endonasal sinus and skull base surgery questionnaire (EES-Q).Methods: Prospectively, 101 patients were included. The EES-Q was completed preoperatively and postoperatively (2 weeks, 3 months, 1 year). Sinonasal complaints were completed daily during the first week postoperatively. Preoperative and postoperative scores were compared. A generalized estimating equation (uni-and multivariate) analysis was performed to identify significant HRQoL changes related to selected covariates.Results: Two weeks postoperatively, physical (p < .05) and social (p < .05) HRQoL are worse and psychological (p < .05) HRQoL improved compared with preoperatively.Three months postoperatively, psychological HRQoL (p = .01) trended back to baseline and no differences in physical or social HRQoL were reported. One year postoperatively, psychological (p = .02) and social (p = .04) HRQoL improved while physical HRQoL remained stable. FA patients report a worse HRQoL preoperatively (social, p < .05) and 3 months postoperatively (social, p < .02 and psychological, p < .02).Sinonasal complaints peak in the first days postoperatively and gradually return to presurgical levels 3 months postoperatively.
Conclusions:The EES-Q provides meaningful information on multidimensional HRQoL to improve patient-centred health care. Social functioning remains the most difficult area in which to achieve improvements. Despite the relatively modest sample size, there is some indication that the FA group continues to show a downward
Objectives: Existing knowledge on Health Related Quality of
Life (HRQoL) after surgical removal of sinonasal inverted papilloma (IP)
is limited. Moreover, predictors for a better or worse postoperative
HRQoL outcome are not known. Our aim was to assess HRQoL in all three
health domains (physical, psychological and social), track its
postoperative trajectory, investigate if preoperative observations could
predict distinct postoperative HRQoL outcomes, and evaluate whether
physicians’ interventions could contribute to improved postoperative
HRQoL. Design: Prospective cohort study. Setting:
Tertiary referral hospital. Participants: Seventy-four patients
who underwent surgery for an IP were included. They were asked to fill
in the Endonasal Endoscopic Sinus and Skull Base Surgery Questionnaire
(EES-Q) preoperatively, and then two weeks, three months, and one year
postoperatively. Main outcome measures: Linear mixed models
(LMM) analyses were performed to evaluate the overall postoperative
HRQoL and the separate health domains, as well as the impact of specific
variables (sex, age, ASA classification, smoker, Krouse staging,
preoperative EES-Q score, type of surgery and postoperative antibiotics)
on HRQoL improvement. Results: The total EES-Q score
(P<.001) as well as the physical (P<.001),
psychological (P=.049), and the social (P=.002) domains significantly
improved postoperatively. ASA classification (P=.049), preoperative
EES-Q score (P<.001) and postoperative antibiotics (P=.036)
were significant variables. Conclusions: Overall HRQoL, as well
as each of the three health domains, improved significantly. A higher
ASA score, a higher preoperative EES-Q score, and the administration of
postoperative antibiotics were significant predictors for better HRQoL
recovery postoperatively. Further research is necessary to confirm these
results.
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