The translocation of high-fired PuOa via the lymphatic system from a simulated puncture wound in the left dorsal metacarpus of beagle dogs was studied. Comparisons were made between dogs with and without excision of the left superficial cervical lymph node. Accumulation of plutonium in the lymph node was determined by counting the low-energy X-ray complex with a thin NaI(T1) detector. The dogs were killed less than 2 weeks after implant and the activity determined for selected tissues. Higher levels of plutonium were found in the liver, spleen and hepatic lymph nodes of lymphadenectomized dogs than in the intact dogs. Implications of these data with regard to therapeutic lymph node removal for workers contaminated with plutonium are discussed.
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