Background: The zone of stasis that forms in acute burn is initially viable, but coagulation progresses to necrosis in the process that follows. Objective: This study investigates the effects of platelet-rich plasma (PRP) on apoptosis in the burn zone of stasis and on the viability of living tissue. Methods: Burns were established in the right ears of 20 female New Zealand rabbits using the "comb burn" model. Platelet-rich plasma was obtained from blood collected from rabbits' ears (n ¼ 10) and was injected subcutaneously into the zone of stasis (n ¼ 10). The same amount of saline solution was injected into the zone of stasis of the control group rabbits (n ¼ 10). Histological and immunohistochemical apoptosis analysis was performed to evaluate viable areas. Results: Apoptosis levels were higher in the control group than in the experimental group. The area of viable tissue in the zone of stasis was greater than in the control group. Infection-induced neutrophil infiltration was statistically significantly lower in the experimental group. Conclusion: In this animal model, apoptosis count and viable tissue area measurement and the antiinflammatory results in the burn area confirm that PRP therapy has a statistically significant positive impact on the survival of the zone of stasis and in acute burn injury. Résumé Historique : La zone de stase qui se forme après une brûlure aiguë est d'abord viable, mais la coagulation entraîne la nécrose dans le processus qui suit. Objectif : La présenteétude porte sur les effets du plasma riche en plaquettes (PRP) sur l'apoptose dans la zone de stase d'une brûlure et sur la viabilité des tissus vivants. Méthodologie : Les chercheurs ontétabli les brûlures dans l'oreille droite de 20 lapins de Nouvelle-Zélande au moyen du modèle de brûlure par peigne. Ils ont obtenu le PRP dans le sang prélevé dans l'oreille des lapins (n ¼ 10) et l'ont injecté par voie sous-cutanée dans la zone de la stase (n ¼ 10). Ils ont injecté la même quantité de soluté physiologique dans la zone de la stase du groupe témoin de lapins (n ¼ 10). Ils ont analysé l'apoptose histologique et immunohistochimique pourévaluer les secteurs viables. Résultats : Les taux d'apoptoseétaient plusélevés dans le groupe témoin que dans le groupe expérimental. La région de tissus viables de la zone de staseétait plusétendue que dans le groupe témoin. L'infiltration de neutrophiles induite par infectionétait statistiquement plus basse dans le groupe expérimental. Conclusion : Dans ce modèle animal, la numération de l'apoptose, la mesure de la région des tissus viables et les résultats anti-inflammatoires dans la région de la brûlure confirment que le traitement par PRP a des répercussions positives statistiquement importantes pour la survie de la zone de stase en cas de brûlure aiguë.
Rhinoplasty is the most challenging facial aesthetic surgical procedure according to many plastic surgeons. Nasal bone osteotomies, especially lateral osteotomies, have a complicated history. If lateral osteotomy is not stable after osteotomy during intraoperative period, stabilization is attempted with internal and external nasal splints but it is not possible to be confident about the stabilization since it is not fully fixed and cannot be observed directly. The authors presented the technique stabilization of the lateral osteotomy inferior tip with cerclage wire, if there is a stabilization problem or step-off deformity after lateral osteotomy.
Related digital media are available in the fulltext version of the article on www.PRSJournal. com. An Assessment of Hernia Formation after Abdominally Based Free Tissue Transfer HarvestB reast reconstruction after oncologic resection is an essential part of health care provision for patients with breast cancer. A growing body of evidence indicates that satisfaction after autologous breast reconstruction is higher when compared with implant-based procedures. 1 However, complications such as hernia formation after abdominal-based flap harvest need to be examined more
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