Introduction: Since the first detection of corona virus disease (COVID-19) cases in Dhaka, Bangladesh on 8 March, 2020, numbers are rising alarmingly. Clinical data on COVID-19 in Bangladesh is lacking. We report early findings on demographic profile, clinical presentations and short-term clinical outcomes of confirmed COVID-19 patients admitted in a large teaching hospital in Dhaka, Bangladesh with preliminary analyses of their association with mortality. Materials and Methods: In this retrospective cross-sectional study, we included reverse transcription polymerase chain reaction (RT-PCR) confirmed COVID-19 patients aged ≥ 15 years, who were admitted in Dhaka Medical College Hospital (DMCH) between May 2 and 15, 2020, the first two weeks when DMCH started admitting COVID-19 patients. Data were collected between May 25 and 29, 2020 from patients or their attendants through telephone interview by a structured questionnaire, after having appropriate consent, irrespective of outcome. One hundred and eight consecutive patients met inclusion criteria through convenient sampling from ward registrar, 102 patients could be reached over phone and data from two patients were discarded in the data cleaning process. The statistical analysis was done by the Statistical Package for the Social Sciences (SPSS) version 22.0. Results: Among the total participants (n=100), mean age was 41.7±16.3 years, 63% were male and 60% patients had positive contact history. Appearance of symptom to hospital admission time was a median of 6 days (range 1 to 21 days) and mean hospital stay was 7.77 ± 5.62 days. Predominant presenting symptoms were fever (69%), cough (54%), breathlessness (41%), fatigue (40%), anorexia (26%) and diarrhea (19%). Hypertension (21%), diabetes mellitus (16%), heart diseases including ischemic heart disease (IHD) (8%) and renal diseases including chronic kidney disease (CKD) (8%) were frequent comorbidities. Ten out of hundred patients died. Older age (p= 0.001), male sex (p= 0.007), smoking (p= 0.001), breathlessness (p=0.001) and presence of comorbidities (p= < 0.05) were significantly associated with mortality. Conclusion: Frequent positive contact history and significant association of breathlessness, smoking and comorbidities with mortality in our study reinforces that abiding by the prevention and containment process, smoking cessation, ensuring proper oxygen therapy and addressing comorbidities adequately are very important measures to mitigate COVID-19 in Bangladesh like the rest of the world. J Bangladesh Coll Phys Surg 2020; 38(0): 29-36
Abstract Abstract Background: Background: Background: Background: Background: Cardiovascular autonomic dysfunction is a serious complication of diabetes mellitus (DM) and is independently associated with microalbuminuria in patients with type-2 DM. This study was conducted to determine the prevalence of cardiovascular autonomic dysfunction in type-2 diabetes patients with microalbuminuria.
Leucocytoclastic vasculitis (LCV) is an isolated condition without systemic vasculitis or glomerulonephritis. The skin is the most commonly involved organ in LCV, predominantly in the lower extremities. The most common skin manifestation is palpable purpura. Some patients may have arthralgias or arthritis as the presenting symptom, usually oligoarthritis of the knees or ankles. The inflammation of small blood vessels, most commonly postcapillary venules, is the cardinal histologic feature of LCV. A16-year-old male admitted into our medicine unit with palpable purpura. He was diagnosed as leukocytoclastic vasculitisof unidentified etiology on the basis of clinical conditions, laboratory tests, and histopathological analysis. Most important cause of LCV is drugs. So, we report this case to increase the awareness of indiscriminate use of medicine which can case this problems. DOI: http://dx.doi.org/10.3329/jom.v13i2.12770 J Medicine 2012; 13 : 240-242
Background: Acute Exacerbation of COPD (AECOPD) is natural course of Chronic ObstructivePulmonary Disease (COPD), where bacterial infection is the major cause. Bacterial infection worse thesign symptoms of the patients and ultimately increase morbidity & mortality. Methods: This is a cross-sectional observational study. 100 clinically diagnosed cases of AECOPD agedbetween 18 and 85 years were included in the study. The sputum specimen was processed by conventionalMethods and subjected to culture and sensitivity in standard laboratory. Results: The prevalence of AECOPD was more common in age group of fifty-six to sixty- five years(38%) with ratio between male and female of 4.6:1. The prevalence of Gram-negative bacteria was 65.21%and Gram-positive bacteria was 34.79%. K. pneumoniae was the commonest bacteria isolated (36.95%)followed by P. aeruginosa (21.73%), S. aureus (15.21), S. pneumoniae (10.86), S. pyogenes and E. coli(6.52%), MRSA (2.17%). The drug sensitivity reveals that 79.55% of the isolates were sensitive to Amikacin(79.55%) followed by Azithromycin (70.45%), Amoxy clavulanic acid (68.18%) and Ciprofloxacin (63.63%). Conclusion: Repeated exacerbation and hospital admission leads to a major impact on the quality of life ofpatients with COPD. Antibiogram helps in screening resistant pathogens and prescribing right treatment protocol. J MEDICINE 2022; 23: 30-35
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