We tried to understand the role of Mitomycin C and Adriamycin in the increased killing of target cells by Cytotoxic T lymphocytes (CTL) and lymphokine activated killers (LAK). For this purpose, we used an objective method allowing quantitative evaluation of the roughness of cell contours on electron micrographs. We compared the folding of the membranes of LAK and CTL as well as conjugated targets exposed to different treatments. We demonstrated first that CTL and LAK displayed similar morphological patterns: the killer cells were more villous than targets in the free areas, and second that the former cells exhibited significant smoothing on the areas of contact with these targets. These results suggest that the binding process (as distinct from the recognition step) is dependent on killer properties which are the same in CTL, LAK and probably NK cells.
Spanish poet, literary critic, and scholar, Jorge Guillén belongs to the Generation of ’27, a group of Spanish poets—which included Federico García Lorca, Rafael Alberti, Pedro Salinas, and others—that emerged in the cultural scene of 1927 beginning with the tribute to Luis Góngora that took place that year in the Ateneo of Seville for the third centenary of his death. Guillén, who was born in Valladolid, Spain, is regarded as one of the greatest Spanish poets of the twentieth century. He attended school in Spain, Switzerland, and Germany, and earned a doctorate from the University of Madrid in 1924. During his career, he lectured at the Sorbonne, Oxford, the universities of Murcia, Seville, Puerto Rico, McGill (Montreal), Harvard, Middlebury College, and Wellesley College. He taught and wrote poetry in the United States for over 20 years, and was a professor at Wellesley until his retirement in 1957. He began writing poetry when he was 16 years old, gaining recognition very early with his first poems, but he left Spain in 1938 after the Generalissimo Francisco Franco took power.
Deleuze and Film is a collection of essays on Gilles Deleuze's filmphilosophy that examines films from around the world, and which demonstrates that Deleuze's thoughts on film are manifold and a tool for thinking on ethics, culture, history, politics, gender, genre, identity, affect, digital aesthetics, and the body. The intention, as the editors state it, is to show that there are as many points of entry into Deleuze's studies on film as there are films. Deleuze and Film, which presents a new generation of authors with 'their own temporality' and shows us the various ways in which the 'field continuous to grow' (3), opens up new frontiers in the interdisciplinary research area of Deleuze studies, including film beyond Europe and USA. At the same time, this collection adds a visual dimension to the existing works in Edinburgh University Press' Deleuze Connections series, establishing the significance of his work as a timeless philosophical device that accounts for the cinematic time and space in question.
The Generation of ’98, a Spanish literary and cultural movement that was active during the first two decades of the 20th century, brought together a group of writers, poets, and intellectuals born between 1864 and 1876, who were against both the politics of the conservative ruling class, as well as the principle of Realism as postulated by the likes of Benito Pérez Galdós and José Echegaray on the literary scene of Madrid at the end of the 19th century.
One of the most important films of Brazil’s Cinema Nôvo movement, Vidas Secas was directed by Nelson Pereira dos Santos, and based on the 1938 novel of the same name written by Graciliano Ramos. It tells the story of a poverty-stricken family in the sertão—the dry Brazilian northeast lands—in the 1940s. Shot in a modernist style reminiscent of Italian neorealist film, Vidas Secas is characterized by telling compositions, subjective shots, atomized, overexposed lighting, and sparse dialogue.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.