This review evaluates the relative efficacy of antimicrobial prophylaxis in patients undergoing colorectal surgery where there is a high risk of surgical wound infection (SWI). Methods Data sources Literature searches of Medline, Embase and the Cochrane Controlled Trials Register were conducted to identify randomised controlled trials (RCTs) published between 1984 and 1995, which investigated antimicrobial prophylaxis in the prevention of postoperative wound infection in patients who had undergone colorectal surgery. Bibliographies of reviews and all identified trials were examined to locate additional studies. A sample of key journals was also handsearched. All languages were considered. Copies State how the article was located, e.g. name the database, handsearching. If an article is to have more than one record, only the first record should list the method of location, for any further records enter Repeat.
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